Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 4/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA3 | P07451 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA6 | P23280 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzo[D]Isoxazole SCHEMBL8438 | 0.97 | — | — | |
| Benzo[D]Isoxazole SCHEMBL29366929 | 0.97 | — | — | |
| Benzo[D]Isoxazole SCHEMBL1355530 | 0.97 | — | — | |
| Benzo[D]Isoxazole SCHEMBL1982876 | 0.95 | TDO2 (0.34) | TDO2CA12CA9NPC1RAB9A | |
| Benzo[D]Isoxazole SCHEMBL29184280 | 0.95 | TDO2 (0.34) | TDO2CA12CA9NPC1RAB9A | |
| Benzo[D]Isoxazole SCHEMBL5778868 | 0.95 | TDO2 (0.34) | TDO2CA12CA9NPC1RAB9A | |
| Benzo[D]Isoxazole SCHEMBL21596877 | 0.95 | TDO2 (0.34) | TDO2CA12CA9NPC1RAB9A | |
| Benzo[D]Isoxazole SCHEMBL28482344 | 0.95 | TDO2 (0.39) | TDO2CA12CA9NPC1RAB9A | |
| Benzo[D]Isoxazole SCHEMBL28915250 | 0.87 | LMNA (0.37) | TDO2NPC1RAB9ALMNAMAPT | |
| Benzo[D]Isoxazole SCHEMBL6649129 | 0.87 | MAPK1 (0.33) | TDO2NPC1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197610-A1 | Benzisoxazoles | JANSSEN PHARMACEUTICA N.V. | 2007-08-23 | — | — | US | disclosed |
| EP-1746991-A2 | DAAO INHIBITING BENZISOXAZOLES FOR TREATING MENTAL DISORDERS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005089753-A2 | DAAO INHIBITING BΞNZISOXAZOLES AND THEIR USE FOR THE TREATMENT OF MENTAL DISORDERS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197610-A1 | Benzisoxazoles | NR4A1, OXER1, NR0B1 | TDO2 1428/4885CA12 4652/4885CA9 2975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.