Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.46 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9787794 | 0.78 | MEN1 (0.52) | OPRK1GAAALDH1A1 | |
| SCHEMBL13419666 | 0.78 | EPHX2 (0.52) | TRPV1GAAALDH1A1HCAR2HDAC2 | |
| SCHEMBL11015718 | 0.77 | ASAH1 (0.52) | GAAHDAC2HDAC8HPGDHDAC1 | |
| SCHEMBL10594495 | 0.77 | ADRB2 (0.51) | OPRK1GAA | |
| SCHEMBL13113999 | 0.76 | SLC6A9 (0.47) | TRPV1OPRM1OPRK1OPRD1GAA | |
| SCHEMBL22265069 | 0.76 | ALDH1A1 (0.49) | TRPV1OPRM1OPRK1OPRD1GAA | |
| SCHEMBL1894742 | 0.75 | TRPV1 (0.82) | TRPV1GAAALDH1A1L3MBTL1ERCC1 | |
| SCHEMBL4151866 | 0.75 | GAA (0.74) | TRPV1GAAL3MBTL1HDAC2HDAC8 | |
| SCHEMBL4151976 | 0.75 | GAA (0.74) | TRPV1GAAL3MBTL1HDAC2HDAC8 | |
| SCHEMBL11269450 | 0.75 | TRPV1 (0.82) | TRPV1GAAALDH1A1L3MBTL1ERCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1750691-A2 | COMPOUNDS FOR TREATMENT OF AIDS AND OTHER DISEASES | New Era Biotech Limited (VG) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005092305-A2 | COMPOUNDS FOR TREATING AIDS AND OTHER DISEASES | NEW ERA BIOTECH LTD (VG) | 2005-10-06 | — | — | WO | disclosed |