Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 8/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 11/20 | 0.41 |
| ▸ | MPEG1 | Q2M385 | 7/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22122179 | 0.71 | TOP1 (0.47) | XIAPALOX5KDM4EALDH1A1MAPT | |
| SCHEMBL9220665 | 0.71 | XIAP (0.54) | XIAPALOX5MPEG1GPR84KDM4E | |
| SCHEMBL5154804 | 0.70 | XIAP (0.54) | XIAPALOX5MPEG1GPR84KDM4E | |
| SCHEMBL12792917 | 0.70 | KDM4E (0.41) | XIAPALOX5MPEG1GPR84KDM4E | |
| SCHEMBL5536618 | 0.70 | AURKA (0.33) | ALDH1A1MAPTHPGDMAPK1MEN1 | |
| SCHEMBL29098299 | 0.69 | XIAP (0.52) | XIAPALOX5MPEG1GPR84KDM4E | |
| SCHEMBL22644817 | 0.69 | KDM4E (0.35) | KDM4EALDH1A1MAPTMEN1ALOX15 | |
| SCHEMBL28363103 | 0.68 | MAPT (0.42) | XIAPKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL29140682 | 0.65 | XIAP (0.48) | XIAPALOX5MPEG1GPR84KDM4E | |
| SCHEMBL28803752 | 0.65 | XIAP (0.48) | XIAPALOX5MPEG1GPR84KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070130702-A1 | Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative | L'OREAL S.A. | 2007-06-14 | — | — | US | claimed |
| EP-1434552-A1 | METHOD FOR DYEING KERATINOUS FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-07-07 | — | — | EP | claimed |
| US-6635090-B1 | Dyeing method using a specific cationic derivative and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative | L'OREAL, S.A. (FR) | 2003-10-21 | — | — | US | claimed |
| WO-2003030841-A1 | METHOD FOR DYEING KERATINOUS FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-04-17 | — | — | WO | claimed |
| US-6458168-B1 | Hair dyeing method using an aliphatic cationic amine and compound chosen from an aldehyde, a ketone, a quinone, a di-imino-isoindoline, and a 3-aminoisoindolone derivative | L'OREAL S.A. (FR) | 2002-10-01 | — | — | US | claimed |
| US-6451067-B1 | HAIR DYE MIXTURE | L'OREAL S.A. (FR) | 2002-09-17 | — | — | US | claimed |
| EP-3843696-B1 | PROCESS AND COMPOSITION FOR COLORING KERATIN FIBERS | OREAL (FR) | 2025-04-09 | — | — | EP | disclosed |
| CN-113164346-B | Composition for keratin fibres comprising a direct dye | 莱雅公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-112601515-B | Method and composition for coloring keratin fibers | 莱雅公司 | 2024-04-05 | — | — | CN | disclosed |
| WO-2024048429-A1 | COSMETIC PROCESS USING PARTICLE WITH MICROPROTRUSION | L'OREAL (FR) | 2024-03-07 | — | — | WO | disclosed |
| WO-2023228870-A1 | COMPOSITION FOR COLORING KERATIN FIBERS | L'OREAL (FR) | 2023-11-30 | — | — | WO | disclosed |
| US-11672743-B2 | Composition for keratin fibers comprising a direct dye | L'OREAL (FR) | 2023-06-13 | — | — | US | disclosed |
| US-20230051189-A1 | COSMETIC PROCESS USING MICRONEEDLE SHEET | L'OREAL (FR) | 2023-02-16 | — | — | US | disclosed |
| WO-2000038641-A1 | DYEING METHOD USING AN ALIPHATIC CATIONIC AMINE AND A ALDEHYDE OR KETONE OR QUINONE OR DI-IMINO-ISOINDOLINE OR 3-AMINO-ISOINDOLONE DERIVATIVES | L'OREAL (FR) | 2000-07-06 | — | — | WO | disclosed |
| WO-2000038639-A1 | DYEING METHOD USING A SPECIFIC CATIONIC DERIVATIVE AND A COMPOUND SELECTED AMONG A SPECIFIC ALDEHYDE, A SPECIFIC KETONE, A QUINONE AND A DI-IMINO-ISOINDOLINE OR 3-AMINO-ISOINDOLONE DERIVATIVE | L'OREAL (FR) | 2000-07-06 | — | — | WO | disclosed |
| WO-2000038640-A1 | HAIR DYEING METHOD USING AN ALIPHATIC CATIONIC AMINE AND A ALDEHYDE OR KETONE OR QUINONE OR DI-IMINO-ISOINDOLINE OR 3-AMINO-ISO-INDOLONE DERIVATIVES | L'OREAL (FR) | 2000-07-06 | — | — | WO | disclosed |
| WO-2000038638-A1 | DYEING METHOD USING A SPECIFIC ACTIVE METHYLENE COMPOUND AND A COMPOUND SELECTED AMONG A SPECIFIC ALDEHYDE, A SPECIFIC KETONE, A QUINONE AND A DI-IMINO-ISOINDOLINE OR 3-AMINO-ISOINDOLONE DERIVATIVE | L'OREAL (FR) | 2000-07-06 | — | — | WO | disclosed |
| EP-0659397-B1 | Process for direct coloration of human keratinic fibers by natural dyes and water steam | OREAL (FR) | 1999-04-14 | — | — | EP | disclosed |
| US-5725603-A | Process for the direct dying of keratinous fibres using natural dyes and water vapor | L'OREAL (FR) | 1998-03-10 | — | — | US | disclosed |
| EP-0659397-A1 | Process for direct coloration of human keratinic fibers by natural dyes and water steam | L'OREAL (FR) | 1995-06-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070130702-A1 | Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative | KRT18, NDUFB5, NDUFB7 | XIAP 1520/4885ALOX5 798/4885MPEG1 3564/4885 |
| US-11672743-B2 | Composition for keratin fibers comprising a direct dye | KRT18, MKI67, DSG1 | XIAP 3522/4885ALOX5 1590/4885MPEG1 4389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.