Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17988138 | 0.82 | — | — | |
| SCHEMBL19140309 | 0.65 | — | — | |
| SCHEMBL577557 | 0.63 | — | — | |
| SCHEMBL10524477 | 0.62 | CA1 (0.33) | PKMTSHRABCG2 | |
| Charcoal, Activated SCHEMBL8437009 | 0.60 | TSHR (0.38) | PKMTSHRABCG2ALDH1A1 | |
| SCHEMBL2404097 | 0.60 | — | — | |
| SCHEMBL8261130 | 0.60 | — | — | |
| SCHEMBL11468155 | 0.60 | — | — | |
| SCHEMBL21088254 | 0.59 | — | — | |
| Ethylene SCHEMBL5491453 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3250550-A1 | COMPOSITIONS AND METHODS FOR VIRAL SENSITIZATION | Ottawa Hospital Research Institute (CA) | 2017-12-06 | — | — | EP | claimed |
| WO-2016119051-A1 | COMPOSITIONS AND METHODS FOR VIRAL SENSITIZATION | OTTAWA HOSPITAL RESEARCH INSTITUTE (CA) | 2016-08-04 | — | — | WO | claimed |
| WO-2016119052-A1 | COMPOSITIONS AND METHODS FOR ENHANCING ONCOLYTIC VIRUS EFFICACY | OTTAWA HOSPITAL RESEARCH INSTITUTE (CA) | 2016-08-04 | — | — | WO | claimed |
| EP-1754514-A1 | Agent and method for colouring keratin fibres | Wella Aktiengesellschaft (DE) | 2007-02-21 | — | — | EP | claimed |
| US-20070000073-A1 | Agent and method for colouring keratin fibres | PROCTER & GAMBLE COMPANY, THE | 2007-01-04 | — | — | US | claimed |
| WO-2006094217-A2 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | THE PROCTER & GAMBLE COMPANY (US) | 2006-09-08 | — | — | WO | claimed |
| US-7070625-B2 | Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives | WELLA AG (DE) | 2006-07-04 | — | — | US | claimed |
| EP-1448540-A1 | AGENT AND METHOD FOR COLORING KERATIN FIBERS CONTAINING 2-BENZOTHIAZOLINONE-HYDRAZONE AND QUINONE DERIVATIVES | Wella Aktiengesellschaft (DE) | 2004-08-25 | — | — | EP | claimed |
| US-20040060124-A1 | Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2004-04-01 | — | — | US | claimed |
| WO-2003042199-A1 | AGENT AND METHOD FOR COLORING KERATIN FIBERS CONTAINING 2-BENZOTHIAZOLINONE-HYDRAZONE AND QUINONE DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2003-05-22 | — | — | WO | claimed |
| US-5879411-A | Composition and method for dyeing keratin fibers with o-benzoquinones and amino- or hydroxy-containing compounds | WELLA AG (DE) | 1999-03-09 | — | — | US | claimed |
| EP-0848942-A1 | Composition and method for dyeing keratin fibres | Wella Aktiengesellschaft (DE) | 1998-06-24 | — | — | EP | claimed |
| US-20220220101-A1 | COMPOSITIONS AND METHODS FOR VIRAL SENSITIZATION | OTTAWA HOSPITAL RESEARCH INSTITUTE (CA) | 2022-07-14 | — | — | US | disclosed |
| US-11339146-B2 | Compositions and methods for viral sensitization | Ottawa Hospital Research Institute and University of Ottawa (CA) | 2022-05-24 | — | — | US | disclosed |
| US-20200354351-A1 | COMPOSITIONS AND METHODS FOR VIRAL SENSITIZATION | OTTAWA HOSPITAL RESEARCH INSTITUTE (CA) | 2020-11-12 | — | — | US | disclosed |
| US-20200207782-A1 | CHEMICALLY ACTIVATED WATER-SOLUBLE PRODRUG | SUMITOMO DAINIPPON PHARMA CO., LTD (JP) | 2020-07-02 | — | — | US | disclosed |
| US-20040060124-A1 | Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2004-04-01 | — | — | US | disclosed |
| WO-2003042199-A1 | AGENT AND METHOD FOR COLORING KERATIN FIBERS CONTAINING 2-BENZOTHIAZOLINONE-HYDRAZONE AND QUINONE DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2003-05-22 | — | — | WO | disclosed |
| US-5879411-A | Composition and method for dyeing keratin fibers with o-benzoquinones and amino- or hydroxy-containing compounds | WELLA AG (DE) | 1999-03-09 | — | — | US | disclosed |
| EP-0848942-A1 | Composition and method for dyeing keratin fibres | Wella Aktiengesellschaft (DE) | 1998-06-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040060124-A1 | Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives | KRT18, NDUFA1, NDUFA2 | PKM 621/4885TSHR 4708/4885ABCG2 1862/4885 |
| US-11339146-B2 | Compositions and methods for viral sensitization | CD4, CD74, HLA-DRB1 | PKM 3457/4885TSHR 4658/4885ABCG2 2717/4885 |
| US-20200207782-A1 | CHEMICALLY ACTIVATED WATER-SOLUBLE PRODRUG | NR0B1, CYP4A11, CYP4B1 | PKM 4553/4885TSHR 600/4885ABCG2 351/4885 |
| US-20220220101-A1 | COMPOSITIONS AND METHODS FOR VIRAL SENSITIZATION | CD4, CD74, HAVCR2 | PKM 3818/4885TSHR 4598/4885ABCG2 3423/4885 |
| US-20070000073-A1 | Agent and method for colouring keratin fibres | KRT18, CDC73, OAT | PKM 734/4885TSHR 4571/4885ABCG2 3012/4885 |
| US-20200354351-A1 | COMPOSITIONS AND METHODS FOR VIRAL SENSITIZATION | CD4, CD74, HAVCR2 | PKM 3818/4885TSHR 4598/4885ABCG2 3423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.