Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 15/20 | 0.52 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4095536 | 0.93 | LTA4H (0.51) | LTA4HSSTR2HRH3 | |
| SCHEMBL7413290 | 0.89 | LTA4H (0.50) | LTA4HCHEK2HRH3 | |
| SCHEMBL7347261 | 0.86 | LTA4H (0.54) | LTA4HCHEK2 | |
| SCHEMBL2185418 | 0.85 | LTA4H (0.50) | LTA4HSSTR2CHEK2 | |
| SCHEMBL5104605 | 0.85 | LTA4H (0.52) | LTA4HCHEK2 | |
| SCHEMBL3647995 | 0.84 | LTA4H (0.53) | LTA4HCHEK2HRH3 | |
| Hydrochloric Acid SCHEMBL5159301 | 0.84 | LTA4H (0.53) | LTA4HCHEK2 | |
| SCHEMBL6005460 | 0.84 | LTA4H (0.49) | LTA4HSSTR2CHEK2 | |
| SCHEMBL13809106 | 0.83 | LTA4H (0.76) | LTA4H | |
| SCHEMBL7326422 | 0.83 | LTA4H (0.76) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1777214-A2 | Novel aryloxy-alkyl-dialkylamines | Wyeth (US) | 2007-04-25 | — | — | EP | disclosed |
| EP-1025077-B1 | NOVEL ARYLOXY-ALKYL-DIALKYLAMINES | WYETH CORP (US) | 2007-02-28 | — | — | EP | disclosed |
| US-6268504-B1 | USED IN THE PRODUCTION OF PHARMACEUTICAL PRODUCTS | AMERICAN HOME PRODUCTS CORPORATION | 2001-07-31 | — | — | US | disclosed |
| US-6242605-B1 | Aryloxy-alkyl-dialkylamines | AMERICAN HOME PRODUCTS CORPORATION | 2001-06-05 | — | — | US | disclosed |
| EP-1025077-A1 | NOVEL ARYLOXY-ALKYL-DIALKYLAMINES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-08-09 | — | — | EP | disclosed |
| US-6005102-A | NOVEL INTERMEDIATES WHICH MAY BE USED IN THE PRODUCTION OF PHARMACEUTICAL COMPOUNDS FOR ANTI-ESTROGENIC AND MATRIX METALLOPROTEINASES-INHIBITING UTILITIES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-12-21 | — | — | US | disclosed |
| WO-1999019293-A1 | NOVEL ARYLOXY-ALKYL-DIALKYLAMINES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-04-22 | — | — | WO | disclosed |