Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 16/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5158495 | 0.93 | LTA4H (0.52) | LTA4HHRH3SSTR2 | |
| SCHEMBL6611442 | 0.82 | LTA4H (0.62) | LTA4H | |
| SCHEMBL7413290 | 0.82 | LTA4H (0.50) | LTA4HHRH3 | |
| SCHEMBL10560161 | 0.80 | LTA4H (0.68) | LTA4H | |
| SCHEMBL28216834 | 0.79 | HRH3 (0.48) | HRH3 | |
| SCHEMBL7347261 | 0.79 | LTA4H (0.54) | LTA4H | |
| SCHEMBL5104605 | 0.78 | LTA4H (0.52) | LTA4H | |
| SCHEMBL5737132 | 0.78 | NFE2L2 (0.53) | LTA4H | |
| SCHEMBL2185418 | 0.78 | LTA4H (0.50) | LTA4HSSTR2 | |
| SCHEMBL5638006 | 0.78 | CHEK2 (0.42) | LTA4HSSTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090111808-A1 | NOVEL HISTAMINE H3-RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS | BIOPROJET (FR) | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111808-A1 | NOVEL HISTAMINE H3-RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS | HRH3, HRH4, HRH1 | LTA4H 672/4885HRH3 1/4885SSTR2 557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.