Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 14/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5158495 | 0.89 | LTA4H (0.52) | LTA4HHRH3CHEK2 | |
| SCHEMBL7347261 | 0.83 | LTA4H (0.54) | LTA4HCHEK2 | |
| SCHEMBL2185418 | 0.83 | LTA4H (0.50) | LTA4HCHEK2 | |
| SCHEMBL5104605 | 0.83 | LTA4H (0.52) | LTA4HCHEK2 | |
| Hydrochloric Acid SCHEMBL5159301 | 0.82 | LTA4H (0.53) | LTA4HCHEK2 | |
| SCHEMBL8796939 | 0.82 | LTA4H (0.52) | LTA4H | |
| SCHEMBL3647995 | 0.82 | LTA4H (0.53) | LTA4HHRH3CHEK2 | |
| SCHEMBL4095536 | 0.82 | LTA4H (0.51) | LTA4HHRH3 | |
| SCHEMBL6005460 | 0.82 | LTA4H (0.49) | LTA4HCHEK2 | |
| SCHEMBL7326422 | 0.81 | LTA4H (0.76) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147080-A1 | ALKYNYL CONTAINING HYDROXAMIC ACID COMPOUNDS AS TACE INHIBITORS | American Cyanamid Company (US) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000044713-A1 | ALKYNYL CONTAINING HYDROXAMIC ACID COMPOUNDS AS TACE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 2000-08-03 | — | — | WO | disclosed |