SCHEMBL515879

SCHEMBL515879

O=C(Oc1c(F)cccc1F)C(=O)Oc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.41
CES2 O00748 3/20 0.39
CES1 P23141 3/20 0.39
SLC2A1 P11166 1/20 0.37
SLC2A4 P14672 1/20 0.37
CYP11B1 P15538 1/20 0.37
CYP11B2 P19099 1/20 0.37
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
HIF1A Q16665 1/20 0.36
ALDH1A1 P00352 2/20 0.35
ALOX15 P16050 1/20 0.35
BCHE P06276 1/20 0.35
GAA P10253 3/20 0.34
RAB9A P51151 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
ALB P02768 1/20 0.33
NPC1 O15118 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ERN1 O75460 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3987193 0.88 CES2 (0.48) KMT2ACES2CES1SLC2A1SLC2A4
SCHEMBL431960 0.78 CYP1A2 (0.38) KMT2ACYP1A2CYP2C9HIF1AALDH1A1
SCHEMBL6476583 0.76 KMT2A (0.46) KMT2ACES2CES1SLC2A1SLC2A4
SCHEMBL15647419 0.75 ALDH1A1 (0.45) KMT2ACES2CES1SLC2A1SLC2A4
SCHEMBL18697360 0.74 CES2 (0.48) KMT2ACES2CES1SLC2A1SLC2A4
SCHEMBL18668623 0.74 CES2 (0.48) KMT2ACES2CES1SLC2A1SLC2A4
SCHEMBL28200073 0.72 KMT2A (0.43) KMT2ACES2CES1SLC2A1SLC2A4
SCHEMBL1994318 0.71 KMT2A (0.49) KMT2ACES2CES1SLC2A1SLC2A4
SCHEMBL15763944 0.69 KMT2A (0.47) KMT2ACES2CES1SLC2A1SLC2A4
SCHEMBL10180032 0.68 KMT2A (0.42) KMT2ACES2CES1SLC2A1SLC2A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240092071-A1 RELEASE LINER FOR SILICONE ADHESIVE LAYER, AND LAMINATE AND ROLL BODY INCLUDING THE RELEASE LINER 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-03-21 US disclosed
EP-4326940-A1 LAMINATE FOR APPLICATION TO WALLPAPER AND ARTICLE USING SAME 3M Innovative Properties Company (US) 2024-02-28 EP disclosed
EP-4284640-A1 RELEASE LINER FOR SILICONE ADHESIVE LAYER, AND LAMINATE AND ROLL BODY INCLUDING THE RELEASE LINER 3M Innovative Properties Company (US) 2023-12-06 EP disclosed
CN-116829667-A Release liner for silicone adhesive layer, and laminate and roll comprising same 3M创新有限公司 2023-09-29 CN disclosed
CN-114829458-B Silicone polyoxamide copolymers having amine-based end groups 3M创新有限公司 2023-06-02 CN disclosed
US-20230054849-A1 SILICONE POLYOXAMIDE COPOLYMERS WITH AMINE-BASED END GROUPS 3M INNOVATIVE PROPERTIES COMPANY 2023-02-23 US disclosed
US-20230039957-A1 SILICONE POLYOXAMIDE COPOLYMERS 3M INNOVATIVE PROPERTIES COMPANY 2023-02-09 US disclosed
CN-111051388-B Hyperbranched polydiorganosiloxane polyoxamide polymers 3M创新有限公司 2022-09-09 CN disclosed
CN-114829458-A Silicone polyoxamide copolymers with amine-based end groups 3M创新有限公司 2022-07-29 CN disclosed
CN-114787243-A Silicone polyoxamide copolymers 3M创新有限公司 2022-07-22 CN disclosed
EP-1963404-A1 POLYDIORGANOSILOXANE POLYOXAMIDE COPOLYMERS 3M Innovative Properties Company (US) 2008-09-03 EP disclosed
EP-1963456-A2 ADHESIVE COMPOSITIONS 3M Innovative Properties Company (US) 2008-09-03 EP disclosed
US-20080199620-A1 ADHESIVE COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY 2008-08-21 US disclosed
US-20080187750-A1 ADHESIVE COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY 2008-08-07 US disclosed
US-7371464-B2 Adhesive compositions 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-05-13 US disclosed
WO-2007075802-A2 ADHESIVE COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-07-05 WO disclosed
WO-2007075317-A1 POLYDIORGANOSILOXANE POLYOXAMIDE COPOLYMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-07-05 WO disclosed
US-20070148474-A1 Block polymers prepared by reacting a copolymer of a polysiloxanediamine, a diamine and oxalic acid with another diamine; clear, heat resistant, elastomeric films 3M INNOVATIVE PROPERTIES COMPANY 2007-06-28 US disclosed
US-20070149745-A1 Polydiorganosiloxane-containing materials with oxalylamino groups 3M INNOVATIVE PROPERTIES COMPANY 2007-06-28 US disclosed
US-20070148475-A1 Adhesive compositions 3M INNOVATIVE PROPERTIES COMPANY 2007-06-28 US disclosed