Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 6/20 | 0.31 |
| ▸ | PPARD | Q03181 | 6/20 | 0.31 |
| ▸ | PPARA | Q07869 | 6/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.31 |
| ▸ | TLR2 | O60603 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5161751 | 0.93 | ALDH1A1 (0.42) | TSHRALDH1A1ADRA1ALMNASLC22A6 | |
| SCHEMBL5162755 | 0.84 | FFAR1 (0.34) | TSHRALDH1A1ADRA1ATDP1FFAR1 | |
| SCHEMBL700717 | 0.81 | TSHR (0.48) | TSHRALDH1A1LMNASLC22A6AKR1B1 | |
| SCHEMBL1972438 | 0.79 | ALDH1A1 (0.50) | TSHRALDH1A1LMNASLC22A6AKR1B1 | |
| SCHEMBL8202305 | 0.79 | LMNA (0.53) | TSHRALDH1A1LMNASLC22A6PRMT1 | |
| SCHEMBL4529885 | 0.77 | ALDH1A1 (0.54) | TSHRALDH1A1ADRA1ALMNASLC22A6 | |
| SCHEMBL4533932 | 0.77 | ALDH1A1 (0.54) | TSHRALDH1A1ADRA1ALMNASLC22A6 | |
| SCHEMBL4522686 | 0.77 | ALDH1A1 (0.54) | TSHRALDH1A1ADRA1ALMNASLC22A6 | |
| SCHEMBL4538058 | 0.77 | ALDH1A1 (0.54) | TSHRALDH1A1ADRA1ALMNASLC22A6 | |
| SCHEMBL4528061 | 0.77 | ALDH1A1 (0.54) | TSHRALDH1A1ADRA1ALMNASLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1207188-B1 | Curable silicone adhesive compositions | GEN ELECTRIC (US) | 2007-03-07 | — | — | EP | disclosed |
| US-6447922-B1 | BIS(TRIALKOXYSILYLALKYL)SUCCINATE ADHESION PROMOTER, A VINYL-CONTAINING POLYDIORGANOSILOXANE, A HYDROGEN-CONTAINING POLYSILOXANE, HYDROSILYLATION CATALYST; ROOM TEMPERATURE VULCANIZABLE | GENERAL ELECTRIC COMPANY | 2002-09-10 | — | — | US | disclosed |
| EP-1207188-A2 | Curable silicone adhesive compositions | GENERAL ELECTRIC COMPANY (US) | 2002-05-22 | — | — | EP | disclosed |