SCHEMBL5162755

SCHEMBL5162755

CO[Si](CCCC(CCC[Si](OC)(OC)OC)(CC(=O)O)C(=O)O)(OC)OC

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.34
CPT2 P23786 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CYP2D6 P10635 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33
SLC13A5 Q86YT5 3/20 0.31
SLC13A2 Q13183 1/20 0.31
SLC13A3 Q8WWT9 1/20 0.31
ALDH1A1 P00352 1/20 0.30
HMGCR P04035 1/20 0.30
CHRM1 P11229 1/20 0.30
TBXA2R P21731 1/20 0.30
ADRA1A P35348 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5159372 0.84 TSHR (0.37) FFAR1TDP1TSHRALDH1A1ADRA1A
SCHEMBL5161751 0.81 ALDH1A1 (0.42) FFAR1TDP1TSHRALDH1A1ADRA1A
SCHEMBL19457979 0.77 FFAR1 (0.31) FFAR1CPT2TDP1
SCHEMBL1882011 0.75
SCHEMBL19458004 0.74
SCHEMBL285165 0.72 TDP1 (0.41) FFAR1CPT2TDP1CYP2D6TSHR
SCHEMBL2720535 0.71 CYP2D6 (0.33) FFAR1CPT2TDP1CYP2D6TSHR
SCHEMBL2138183 0.71 TDP1 (0.45) FFAR1CPT2TDP1TSHRALDH1A1
SCHEMBL27938400 0.71 TDP1 (0.40) FFAR1CPT2TDP1CYP2D6TSHR
SCHEMBL700717 0.70 TSHR (0.48) FFAR1TDP1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1207188-B1 Curable silicone adhesive compositions GEN ELECTRIC (US) 2007-03-07 EP claimed
US-6447922-B1 BIS(TRIALKOXYSILYLALKYL)SUCCINATE ADHESION PROMOTER, A VINYL-CONTAINING POLYDIORGANOSILOXANE, A HYDROGEN-CONTAINING POLYSILOXANE, HYDROSILYLATION CATALYST; ROOM TEMPERATURE VULCANIZABLE GENERAL ELECTRIC COMPANY 2002-09-10 US claimed
EP-1207188-A2 Curable silicone adhesive compositions GENERAL ELECTRIC COMPANY (US) 2002-05-22 EP claimed
EP-1207188-B1 Curable silicone adhesive compositions GEN ELECTRIC (US) 2007-03-07 EP disclosed
US-6447922-B1 BIS(TRIALKOXYSILYLALKYL)SUCCINATE ADHESION PROMOTER, A VINYL-CONTAINING POLYDIORGANOSILOXANE, A HYDROGEN-CONTAINING POLYSILOXANE, HYDROSILYLATION CATALYST; ROOM TEMPERATURE VULCANIZABLE GENERAL ELECTRIC COMPANY 2002-09-10 US disclosed
EP-1207188-A2 Curable silicone adhesive compositions GENERAL ELECTRIC COMPANY (US) 2002-05-22 EP disclosed
US-4273698-A Self-bonding room temperature vulcanizable silicone rubber compositions GENERAL ELECTRIC COMPANY (US) 1981-06-16 US disclosed