SCHEMBL5159922

SCHEMBL5159922

C=CC(=O)OC(C)C1NCCO1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7112803 0.81
SCHEMBL1440239 0.78 ALDH1A1 (0.36) TSHR
SCHEMBL8552958 0.76 SLC6A2 (0.36) TSHR
SCHEMBL11188435 0.76 TSHR (0.45) TSHR
SCHEMBL19834858 0.73 TSHR (0.36) TSHR
SCHEMBL10870459 0.73 TSHR (0.38) TSHR
SCHEMBL1504293 0.73 TSHR (0.38) TSHR
SCHEMBL238952 0.73 TSHR (0.38) TSHR
SCHEMBL11188431 0.73 TSHR (0.32) TSHR
Ethylene SCHEMBL27409771 0.71 TSHR (0.37) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018017570-A1 A HAIR STRAIGHTENING AND STYLING COMPOSITION, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2018-01-25 WO claimed
US-7235595-B2 Aqueous traffic paint and method of application ROHM AND HAAS COMPANY (US) 2007-06-26 US claimed
EP-1505127-B1 Aqueous traffic paint and method of application ROHM & HAAS (US) 2005-11-09 EP claimed
US-20050032933-A1 Aqueous traffic paint and method of application ROHM AND HAAS COMPANY 2005-02-10 US claimed
EP-1505127-A1 Aqueous traffic paint and method of application ROHM AND HAAS COMPANY (US) 2005-02-09 EP claimed
EP-0036294-A2 Polymer of acrylic acid oligomer, its preparation and use in coating and/or impregnating compositions and the moderation of copolymer glass transition temperature using the oligomer ROHM AND HAAS COMPANY (US) 1981-09-23 EP claimed
US-4158736-A ANIONIC POLYMERIZATION ROHM AND HAAS COMPANY (US) 1979-06-19 US claimed
US-20250032398-A1 HIGH MOLECULAR WEIGHT BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHILIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2025-01-30 US disclosed
WO-2023102600-A1 SYNTHESIS OF AMPHIPHILIC BLOCK COPOLYMERS AND POLYMERIC NANOFIBERS PRODUCED THEREFROM NEWSOUTH INNOVATIONS PTY LIMITED (AU) 2023-06-15 WO disclosed
EP-3356480-B1 SHELF-STABLE AQUEOUS COMPOSITION AND PROCESS OF MAKING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2021-01-06 EP disclosed
US-10717879-B2 Shelf-stable aqueous composition and process of making the same DOW GLOBAL TECHNOLOGIES LLC (US) 2020-07-21 US disclosed
US-20190382519-A1 CROSS-LINKED BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES, COMPOSITIONS, AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2019-12-19 US disclosed
US-20180340077-A1 SHELF-STABLE AQUEOUS COMPOSITION AND PROCESS OF MAKING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2018-11-29 US disclosed
US-4158736-A ANIONIC POLYMERIZATION ROHM AND HAAS COMPANY (US) 1979-06-19 US disclosed
US-4141868-A DICYCLOPENTENYLOXYALKYLENE ACRYLATE REACTIVE MONOMER, ADDITION POLYMER ROHM AND HAAS COMPANY (US) 1979-02-27 US disclosed
US-4131580-A OXIDATIVE CURING CATALYST ROHM AND HAAS COMPANY (US) 1978-12-26 US disclosed
US-4119600-A ANIONICALLY-STABILIZED POLYMER LATEX, WATER-SOLUBLE POLYMER, VOLATILE BASE ROHM AND HAAS COMPANY (US) 1978-10-10 US disclosed
US-4097677-A INTERMEDIATES FOR ADDITION POLYMERS USED IN COATING AND MOLDING PROCESSES ROHM AND HAAS COMPANY (US) 1978-06-27 US disclosed
US-4060529-A Polymerization inhibitors for N-substituted aminoalkyl acrylic monomers ROHM AND HAAS COMPANY (US) 1977-11-29 US disclosed
US-4054717-A CLAYS, WATER SOLUBLE POLYMER HAVING AMINE GROUPS ROHM AND HAAS COMPANY (US) 1977-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190382519-A1 CROSS-LINKED BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES, COMPOSITIONS, AND APPLICATIONS THEREOF ADSL, ABHD6, APH1B TSHR 4275/4885
US-20250032398-A1 HIGH MOLECULAR WEIGHT BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHILIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF PCNA, ADSL, APH1B TSHR 3587/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.