Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 4/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5163398 | 0.88 | ITGB1 (0.44) | PTGDR2ITGB1ITGA4MAOBHTR2C | |
| SCHEMBL5178697 | 0.87 | PTGDR2 (0.34) | PTGDR2FFAR2NPC1MAPTRAB9A | |
| SCHEMBL5160838 | 0.84 | ITGB1 (0.49) | ITGB1ITGA4MAOBHTR2C | |
| SCHEMBL5407542 | 0.83 | ITGA4 (0.36) | PTGDR2FFAR2ITGB1ITGA4HTR1A | |
| SCHEMBL5160946 | 0.83 | ITGB1 (0.43) | ITGB1ITGA4MAPTMAOBHTR2C | |
| SCHEMBL5158931 | 0.81 | ITGA4 (0.37) | PTGDR2FFAR2ITGB1ITGA4HTR1A | |
| SCHEMBL5160876 | 0.81 | ITGB1 (0.33) | FFAR2ITGB1ITGA4NPC1MAPT | |
| SCHEMBL5158473 | 0.78 | ITGB1 (0.42) | ITGB1ITGA4DRD2DRD3HTR2C | |
| SCHEMBL14371606 | 0.78 | ITGA4 (0.40) | PTGDR2ITGB1ITGA4 | |
| SCHEMBL14608580 | 0.78 | ITGA4 (0.37) | PTGDR2ITGB1ITGA4MAOBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232601-A1 | Vla-4 Inhibitor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-10-04 | — | — | US | disclosed |
| EP-1757602-A1 | VLA-4 INHIBITOR | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232601-A1 | Vla-4 Inhibitor | VCAM1, ITGB4, ITGA4 | PTGDR2 2692/4885FFAR2 1197/4885ITGB1 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.