Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5392456 | 0.84 | TSHR (0.33) | TSHR | |
| SCHEMBL5160714 | 0.81 | TSHR (0.34) | TSHR | |
| SCHEMBL5162260 | 0.81 | TSHR (0.31) | TSHR | |
| SCHEMBL3943493 | 0.79 | TSHR (0.34) | TSHR | |
| SCHEMBL5386698 | 0.78 | ALDH1A1 (0.34) | TSHR | |
| SCHEMBL5398742 | 0.78 | TSHR (0.37) | TSHR | |
| SCHEMBL3946203 | 0.78 | TSHR (0.33) | TSHR | |
| SCHEMBL5160547 | 0.77 | TSHR (0.31) | TSHR | |
| SCHEMBL5160540 | 0.76 | HTR2C (0.47) | — | |
| SCHEMBL5391855 | 0.74 | LMNA (0.38) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406874-B1 | COMPOUNDS DERIVED FROM DIAMINOPYRAZOLES SUBSTITUTED BY AN AMINOALKYL OR AMINOALKENYL RADICAL AND THEIR USE IN OXIDATION DYEING OF KERATINOUS FIBRES | OREAL (FR) | 2007-03-28 | — | — | EP | claimed |
| US-7014663-B2 | Compounds derived from diaminopyrazoles substituted by an aminoalkyl or aminoalkenyl radical and their use in oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2006-03-21 | — | — | US | claimed |
| US-20050015893-A1 | Compounds derived from diaminopyrazoles substituted by an aminoalkyl or aminoalkenyl radical and their use in oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2005-01-27 | — | — | US | claimed |
| EP-1406874-A1 | COMPOUNDS DERIVED FROM DIAMINOPYRAZOLES SUBSTITUTED BY AN AMINOALKYL OR AMINOALKENYL RADICAL AND THEIR USE IN OXIDATION DYEING OF KERATINOUS FIBRES | L'OREAL (FR) | 2004-04-14 | — | — | EP | claimed |
| WO-2003008385-A1 | COMPOUNDS DERIVED FROM DIAMINOPYRAZOLES SUBSTITUTED BY AN AMINOALKYL OR AMINOALKENYL RADICAL AND THEIR USE IN OXIDATION DYEING OF KERATINOUS FIBRES | L'OREAL (FR) | 2003-01-30 | — | — | WO | claimed |
| US-7014663-B2 | Compounds derived from diaminopyrazoles substituted by an aminoalkyl or aminoalkenyl radical and their use in oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2006-03-21 | — | — | US | disclosed |
| US-20050015893-A1 | Compounds derived from diaminopyrazoles substituted by an aminoalkyl or aminoalkenyl radical and their use in oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050015893-A1 | Compounds derived from diaminopyrazoles substituted by an aminoalkyl or aminoalkenyl radical and their use in oxidation dyeing of keratinous fibres | KRT18, AOC1, AKR1C3 | TSHR 4546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.