SCHEMBL5161565

SCHEMBL5161565

O=C(ON1CCCCC1)C(O)(c1ccccc1)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 3/20 0.49
CHRM2 P08172 2/20 0.47
CHRM1 P11229 2/20 0.47
ALDH1A1 P00352 1/20 0.47
CHRM4 P08173 1/20 0.47
CHRM5 P08912 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6434933 0.98 CHRM3 (0.50) CHRM3CHRM2CHRM1ALDH1A1CHRM4
SCHEMBL27768710 0.78 HPGD (0.45) ALDH1A1
SCHEMBL28495717 0.75 HPGD (0.53) ALDH1A1
SCHEMBL1249246 0.75 HPGD (0.53) ALDH1A1
Piperilate SCHEMBL26493 0.74 ALDH1A1 (0.78) CHRM3CHRM2CHRM1ALDH1A1CHRM4
SCHEMBL29098438 0.74 HPGD (0.52) ALDH1A1
SCHEMBL2510973 0.73 KMT2A (0.50) ALDH1A1
Piperilate SCHEMBL1650954 0.73 ALDH1A1 (0.76) CHRM3CHRM2CHRM1ALDH1A1CHRM4
SCHEMBL11151698 0.72 KCNN4 (0.35) CHRM3ALDH1A1
SCHEMBL11878020 0.72 CHRM3 (0.49) CHRM3CHRM2CHRM1ALDH1A1CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1275645-B1 LABELED COMPOUNDS FOR MEASURING THE FUNCTION OF THE MUSCARINIC ACETYLCHOLINE NERVOUS SYSTEM HAMAMATSU PHOTONICS KK (JP) 2007-02-28 EP claimed
US-6649142-B2 Labeled compounds for measuring the function of the muscarinic acetylcholine nervous system HAMAMATSU PHOTONICS K.K. (JP) 2003-11-18 US claimed
US-20030113261-A1 Labeled compounds for measuring the function of the muscarinic acetylcholine nervous system HAMAMATSU PHOTONICS K.K. (JP) 2003-06-19 US claimed
EP-1275645-A1 LABELED COMPOUNDS FOR MEASURING THE FUNCTION OF THE MUSCARINIC ACETYLCHOLINE NERVOUS SYSTEM HAMAMATSU PHOTONICS K. K. (JP) 2003-01-15 EP claimed
WO-2015157138-A1 ABUSE-DETERRENT CONTROLLED RELEASE FORMULATIONS BANNER LIFE SCIENCES LLC (US) 2015-10-15 WO disclosed
EP-1275645-B1 LABELED COMPOUNDS FOR MEASURING THE FUNCTION OF THE MUSCARINIC ACETYLCHOLINE NERVOUS SYSTEM HAMAMATSU PHOTONICS KK (JP) 2007-02-28 EP disclosed
US-6649142-B2 Labeled compounds for measuring the function of the muscarinic acetylcholine nervous system HAMAMATSU PHOTONICS K.K. (JP) 2003-11-18 US disclosed
US-20030113261-A1 Labeled compounds for measuring the function of the muscarinic acetylcholine nervous system HAMAMATSU PHOTONICS K.K. (JP) 2003-06-19 US disclosed
EP-1275645-A1 LABELED COMPOUNDS FOR MEASURING THE FUNCTION OF THE MUSCARINIC ACETYLCHOLINE NERVOUS SYSTEM HAMAMATSU PHOTONICS K. K. (JP) 2003-01-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030113261-A1 Labeled compounds for measuring the function of the muscarinic acetylcholine nervous system CHRM3, CHRM5, CHRM2 CHRM3 1/4885CHRM2 3/4885CHRM1 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.