Piperilate

Piperilate

SCHEMBL26493

O=C(OCCN1CCCCC1)C(O)(c1ccccc1)c1ccccc1

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.78
KMT2A Q03164 3/20 0.70
MEN1 O00255 2/20 0.70
GAA P10253 1/20 0.70
KDM4E B2RXH2 2/20 0.69
HTT P42858 1/20 0.58
CHRM2 P08172 4/20 0.54
CHRM1 P11229 4/20 0.54
CYP2D6 P10635 3/20 0.54
HTR1A P08908 2/20 0.54
OPRM1 P35372 2/20 0.54
KCNH2 Q12809 2/20 0.54
LMNA P02545 2/20 0.54
CHRM4 P08173 3/20 0.53
CHRM5 P08912 3/20 0.53
CHRM3 P20309 3/20 0.53
MAPK1 P28482 2/20 0.52
BCHE P06276 1/20 0.52
DRD2 P14416 1/20 0.51
DRD1 P21728 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Piperilate SCHEMBL1650954 0.99 ALDH1A1 (0.76) ALDH1A1KMT2AMEN1GAAKDM4E
Piperilate SCHEMBL1316709 0.94 ALDH1A1 (0.73) ALDH1A1KMT2AMEN1GAAKDM4E
SCHEMBL25142218 0.82 ALDH1A1 (0.57) ALDH1A1KMT2AMEN1GAAKDM4E
SCHEMBL3361921 0.78 HTT (0.54) ALDH1A1KMT2AMEN1GAAKDM4E
SCHEMBL3365837 0.77 ALDH1A1 (0.54) ALDH1A1KMT2AMEN1GAAKDM4E
SCHEMBL9588270 0.77 ALDH1A1 (0.68) ALDH1A1KMT2AMEN1GAAKDM4E
SCHEMBL5248057 0.76 ALDH1A1 (0.48) ALDH1A1KMT2AMEN1GAAKDM4E
SCHEMBL501868 0.76 KMT2A (0.75) ALDH1A1KMT2AMEN1KDM4ECYP2D6
SCHEMBL5248621 0.76 ALDH1A1 (0.47) ALDH1A1KMT2AMEN1GAAKDM4E
SCHEMBL5245039 0.76 ALDH1A1 (0.50) ALDH1A1KMT2AMEN1GAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 567 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190125734-A1 COMPOSITION FOR TREATING OR PREVENTING ATOPIC DERMATITIS NANOEGG RESEARCH LABORATORIES, INC. (JP) 2019-05-02 US claimed
EP-3456353-A1 COMPOSITION FOR TREATING OR PREVENTING ATOPIC DERMATITIS Nanoegg Research Laboratories, Inc. (JP) 2019-03-20 EP claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
EP-1879578-A4 METHODS AND COMPOSITIONS FOR THE TREATMENT OF URINARY INCONTINENCE DOV PHARMACEUTICAL INC (US) 2009-05-13 EP claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
EP-1879578-A2 METHODS AND COMPOSITIONS FOR THE TREATMENT OF URINARY INCONTINENCE DOV Pharmaceutical Inc. (US) 2008-01-23 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
WO-2006102029-A9 METHODS AND COMPOSITIONS FOR THE TREATMENT OF URINARY INCONTINENCE DOV PHARMACEUTICAL INC (US) 2006-12-07 WO claimed
WO-2006102029-A2 METHODS AND COMPOSITIONS FOR THE TREATMENT OF URINARY INCONTINENCE DOV PHARMACEUTICAL, INC. (US) 2006-09-28 WO claimed
EP-1273301-B1 Pharmaceutical preparations based on active ingredients susceptible to illicit administration ALTERGON SA (CH) 2006-09-06 EP claimed
EP-0729748-B1 PROCESS FOR PRODUCING STABLE MEDICINAL COMPOSITION NIPPON SHINYAKU CO LTD (JP) 2003-02-26 EP claimed
EP-1273301-A2 Pharmaceutical preparations based on active ingredients susceptible to illicit administration ALTERGON S.A. (CH) 2003-01-08 EP claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
JP-5132431-A None JP disclosed
US-3978216-A AMINOOXYACETIC ACID NELSON RESEARCH & DEVELOPMENT COMPANY (US) 1976-08-31 US disclosed
US-3947579-A HALOGENATED AMINO ACID NELSON RESEARCH & DEVELOPMENT COMPANY (US) 1976-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190125734-A1 COMPOSITION FOR TREATING OR PREVENTING ATOPIC DERMATITIS CHRM3, ACHE, CHRNB1 ALDH1A1 1959/4885KMT2A 1813/4885MEN1 3999/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.