Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 3/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5161565 | 0.98 | CHRM3 (0.49) | CHRM3CHRM2CHRM1ALDH1A1CHRM4 | |
| SCHEMBL27768710 | 0.76 | HPGD (0.45) | ALDH1A1 | |
| SCHEMBL2510973 | 0.74 | KMT2A (0.50) | ALDH1A1 | |
| SCHEMBL11878020 | 0.73 | CHRM3 (0.49) | CHRM3CHRM2CHRM1ALDH1A1CHRM4 | |
| SCHEMBL1249246 | 0.73 | HPGD (0.53) | ALDH1A1 | |
| SCHEMBL28495717 | 0.73 | HPGD (0.53) | ALDH1A1 | |
| Piperilate SCHEMBL26493 | 0.72 | ALDH1A1 (0.78) | CHRM3CHRM2CHRM1ALDH1A1CHRM4 | |
| SCHEMBL29098438 | 0.71 | HPGD (0.52) | ALDH1A1 | |
| Piperilate SCHEMBL1650954 | 0.71 | ALDH1A1 (0.76) | CHRM3CHRM2CHRM1ALDH1A1CHRM4 | |
| SCHEMBL1871564 | 0.70 | CHRM3 (0.61) | CHRM3CHRM2CHRM1CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1589959-A2 | METHODS OF TREATING LOWER URINARY TRACT DISORDERS USING SODIUM CHANNEL MODULATORS | Dynogen Pharmaceuticals Inc. (US) | 2005-11-02 | — | — | EP | disclosed |
| WO-2004066990-A2 | METHODS OF TREATING LOWER URINARY TRACT DISORDERS USING SODIUM CHANNEL MODULATORS | DYNOGEN PHARMACEUTICALS, INC. (US) | 2004-08-12 | — | — | WO | disclosed |