Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 8/20 | 0.32 |
| ▸ | HTR2C | P28335 | 8/20 | 0.32 |
| ▸ | HTR2B | P41595 | 3/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3943493 | 0.88 | TSHR (0.34) | TSHRHTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL5160547 | 0.81 | TSHR (0.31) | TSHR | |
| SCHEMBL5160540 | 0.81 | HTR2C (0.47) | HTR2AHTR2CHTR2BHTR1AADRA2A | |
| SCHEMBL6068577 | 0.81 | SMPD3 (0.31) | HTR2AHTR2CHTR2B | |
| SCHEMBL5386512 | 0.80 | CSNK2A1 (0.35) | TSHRHTR2AHTR2CHTR2B | |
| SCHEMBL5429792 | 0.80 | — | — | |
| SCHEMBL5386698 | 0.79 | ALDH1A1 (0.34) | TSHRSMN1; SMN2 | |
| SCHEMBL5398742 | 0.79 | TSHR (0.37) | TSHRHTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL5160985 | 0.78 | HTR2A (0.35) | TSHRHTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL5418599 | 0.76 | HTR2C (0.34) | TSHRHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406874-B1 | COMPOUNDS DERIVED FROM DIAMINOPYRAZOLES SUBSTITUTED BY AN AMINOALKYL OR AMINOALKENYL RADICAL AND THEIR USE IN OXIDATION DYEING OF KERATINOUS FIBRES | OREAL (FR) | 2007-03-28 | — | — | EP | claimed |
| US-7014663-B2 | Compounds derived from diaminopyrazoles substituted by an aminoalkyl or aminoalkenyl radical and their use in oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2006-03-21 | — | — | US | claimed |
| US-20050015893-A1 | Compounds derived from diaminopyrazoles substituted by an aminoalkyl or aminoalkenyl radical and their use in oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2005-01-27 | — | — | US | claimed |
| EP-1406874-A1 | COMPOUNDS DERIVED FROM DIAMINOPYRAZOLES SUBSTITUTED BY AN AMINOALKYL OR AMINOALKENYL RADICAL AND THEIR USE IN OXIDATION DYEING OF KERATINOUS FIBRES | L'OREAL (FR) | 2004-04-14 | — | — | EP | claimed |
| WO-2003008385-A1 | COMPOUNDS DERIVED FROM DIAMINOPYRAZOLES SUBSTITUTED BY AN AMINOALKYL OR AMINOALKENYL RADICAL AND THEIR USE IN OXIDATION DYEING OF KERATINOUS FIBRES | L'OREAL (FR) | 2003-01-30 | — | — | WO | claimed |
| US-7250063-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2007-07-31 | — | — | US | disclosed |
| US-7014663-B2 | Compounds derived from diaminopyrazoles substituted by an aminoalkyl or aminoalkenyl radical and their use in oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2006-03-21 | — | — | US | disclosed |
| US-20050015893-A1 | Compounds derived from diaminopyrazoles substituted by an aminoalkyl or aminoalkenyl radical and their use in oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050015893-A1 | Compounds derived from diaminopyrazoles substituted by an aminoalkyl or aminoalkenyl radical and their use in oxidation dyeing of keratinous fibres | KRT18, AOC1, AKR1C3 | TSHR 4546/4885HTR2A 4208/4885HTR2C 2134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.