Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3272500 | 0.81 | OPRM1 (0.41) | SLC6A4SLC6A3OPRM1 | |
| SCHEMBL1625474 | 0.80 | OPRM1 (0.49) | SLC6A4SLC6A3OPRM1MEN1NPC1 | |
| SCHEMBL19331078 | 0.80 | WDR5 (0.38) | OPRM1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL11711562 | 0.80 | OPRM1 (0.43) | OPRM1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL21874212 | 0.79 | ALDH1A1 (0.50) | SLC6A4SLC6A3OPRM1MEN1NPC1 | |
| SCHEMBL10317539 | 0.79 | OPRM1 (0.46) | SLC6A4SLC6A3OPRM1 | |
| SCHEMBL25933959 | 0.73 | OPRM1 (0.53) | OPRM1ALDH1A1LMNA | |
| SCHEMBL21964253 | 0.72 | OPRM1 (0.41) | SLC6A4SLC6A3OPRM1POLB | |
| SCHEMBL19330985 | 0.70 | WDR5 (0.36) | OPRM1 | |
| SCHEMBL14893610 | 0.70 | OPRM1 (0.35) | OPRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747210-A1 | 3- OR 4-MONOSUBSTITUTED PHENOL AND THIOPHENOL DERIVATIVES USEFUL AS H3 LIGANDS | Warner-Lambert Company LLC (US) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005108384-A1 | 3- OR 4-MONOSUBSTITUTED PHENOL AND THIOPHENOL DERIVATIVES USEFUL AS H3 LIGANDS | WARNER-LAMBERT COMPANY LLC (US) | 2005-11-17 | — | — | WO | disclosed |