Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.58 |
| ▸ | STAT3 | P40763 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | PPARD | Q03181 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30764700 | 1.00 | ATM (0.66) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL80667 | 0.88 | ATM (0.61) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL16641094 | 0.87 | CYP19A1 (0.77) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL31157848 | 0.87 | CYP19A1 (0.77) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL27200220 | 0.85 | ATM (0.58) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL10411628 | 0.85 | ATM (0.58) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL10335393 | 0.85 | CYP19A1 (0.81) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL3792476 | 0.84 | MAPT (0.53) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL30413844 | 0.84 | MAPT (0.53) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL11340554 | 0.84 | CRHBP (0.47) | ATMKDM4ECA2POLBCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102911175-B | Preparation method of 2-amino-4-carbonyl-7-(3,4-dimethoxybenzyl)-5-vinyl-6,7-dihydro-3H-pyrrolo-[2,3-d]pyrimidine | NANJING EAST SUNSCREEN PHARMACEUTICAL CO LTD | 2015-04-15 | — | — | CN | claimed |
| CN-102911175-A | Preparation method of 2-amino-4-carbonyl-7-(3,4-dimethoxybenzyl)-5-vinyl-6,7-dihydro-3H-pyrrolo-[2,3-d]pyrimidine | NANJING EAST SUNSCREEN PHARMACEUTICAL CO LTD | 2013-02-06 | — | — | CN | claimed |
| US-20250388592-A1 | (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | REMYND N.V. (BE) | 2025-12-25 | — | — | US | disclosed |
| US-20250248955-A1 | PHENYL ACRYLIC ACID COMPOUND, AND PREPARATION METHOD AND APPLICATION THEREOF | LONGIVITRON (SUZHOU) BIOTECHNOLOGY CO., LTD (CN) | 2025-08-07 | — | — | US | disclosed |
| EP-4512796-A1 | PHENYL ACRYLIC ACID COMPOUND, AND PREPARATION METHOD AND APPLICATION THEREOF | Longivitron (Suzhou) Biotechnology Co., Ltd (CN) | 2025-02-26 | — | — | EP | disclosed |
| US-20250011295-A1 | USE OF 3-ARYLPHTHALIDES AND DERIVATIVES THEREOF AS ANTI-INFLAMMATORY AGENTS | UNIVERSIDAD DE CÁDIZ (ES) | 2025-01-09 | — | — | US | disclosed |
| EP-4378933-A1 | USE OF 3-ARYLPHTHALIDES AND DERIVATIVES THEREOF AS ANTI-INFLAMMATORY AGENTS | Universidad de Cádiz (ES) | 2024-06-05 | — | — | EP | disclosed |
| WO-2024033479-A1 | (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | REMYND N.V. (BE) | 2024-02-15 | — | — | WO | disclosed |
| CN-114644560-B | Phenyl acrylic compound and preparation method and application thereof | 朗捷睿(苏州)生物科技有限公司 | 2024-02-02 | — | — | CN | disclosed |
| WO-2023202559-A1 | PHENYL ACRYLIC ACID COMPOUND, AND PREPARATION METHOD AND APPLICATION THEREOF | 朗捷睿(苏州)生物科技有限公司 | 2023-10-26 | — | — | WO | disclosed |
| WO-2023007042-A1 | USE OF 3-ARYLPHTHALIDES AND DERIVATIVES THEREOF AS ANTI-INFLAMMATORY AGENTS | UNIVERSIDAD DE CÁDIZ (ES) | 2023-02-02 | — | — | WO | disclosed |
| EP-0011483-B1 | AZOCINE COMPOUNDS SUITABLE AS ANALGESICS, AND PROCESS FOR THEIR PRODUCTION | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1983-01-26 | — | — | EP | disclosed |
| US-4353900-A | HYPOTENSIVE, ANTIARRHYTHMIA, CARDIOTONIC, VASODILATORS | SYNTEX (U.S.A.) INC. (US) | 1982-10-12 | — | — | US | disclosed |
| US-4294834-A | Azocine analgesics and method for their preparation | GODECKE AKTIENGESELLSCHAFT (DE) | 1981-10-13 | — | — | US | disclosed |
| EP-0030749-A1 | Carboximidamide derivatives, a process for preparing them and pharmaceutical preparations containing same | AKZO N.V. (NL) | 1981-06-24 | — | — | EP | disclosed |
| US-4258062-A | ISOPRENALINE ANTAGONISTS EFFECTING HEART RATE AND BLOOD PRESSURE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-03-24 | — | — | US | disclosed |
| EP-0011483-A1 | Azocine compounds suitable as analgesics, and process for their production | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1980-05-28 | — | — | EP | disclosed |
| US-4171370-A | Phenoxy-amino-propanols | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-10-16 | — | — | US | disclosed |
| US-3987200-A | INOTROPIC AGENTS, 3,4-DIHYDROXY-PHENYL-ALKYL PHENETHYLAMINE | ELI LILLY AND COMPANY (US) | 1976-10-19 | — | — | US | disclosed |
| US-3936462-A | CNS DEPRESSANT, ANALGESIC | STERLING DRUG INC. (US) | 1976-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250011295-A1 | USE OF 3-ARYLPHTHALIDES AND DERIVATIVES THEREOF AS ANTI-INFLAMMATORY AGENTS | DPP4, DPP3, NFKBIA | ATM 4285/4885KDM4E 1268/4885CA2 2870/4885 |
| US-20250388592-A1 | (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | SNCA, CHRNA6, CHRNA5 | ATM 4122/4885KDM4E 4138/4885CA2 1348/4885 |
| US-20250248955-A1 | PHENYL ACRYLIC ACID COMPOUND, AND PREPARATION METHOD AND APPLICATION THEREOF | APP, DDC, AGER | ATM 246/4885KDM4E 1587/4885CA2 4427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.