Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ5 | P48544 | 1/20 | 0.56 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.54 |
| ▸ | RORC | P51449 | 3/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5163528 | 0.86 | MAPT (0.56) | PTGS1L3MBTL1MEN1MAPTKMT2A | |
| SCHEMBL5161551 | 0.85 | GAA (0.55) | RORCMEN1MAPTKMT2A | |
| SCHEMBL5164480 | 0.83 | CYP1A1 (0.45) | RORCNLRP3MEN1MAPTKMT2A | |
| SCHEMBL5163733 | 0.82 | KMT2A (0.53) | L3MBTL1NLRP3MEN1MAPTKMT2A | |
| SCHEMBL5163718 | 0.82 | JAK2 (0.49) | MAPTANO1 | |
| SCHEMBL5161594 | 0.82 | KMT2A (0.55) | MEN1MAPTKMT2A | |
| SCHEMBL5164381 | 0.82 | POLB (0.53) | EPHX2NLRP3MEN1MAPTKMT2A | |
| SCHEMBL5162952 | 0.81 | CYP1A2 (0.54) | KCNJ5KCNJ3EPHX2L3MBTL1MEN1 | |
| SCHEMBL5162110 | 0.81 | GAA (0.43) | RORCEPHX2MEN1MAPTKMT2A | |
| Ammonia Solution, Strong SCHEMBL5309981 | 0.80 | CYP1A2 (0.53) | KCNJ5KCNJ3EPHX2L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070067923-A1 | 1,3-Diaminobenzene derivatives and colorants comprising these compounds | PROCTER & GAMBLE COMPANY, THE | 2007-03-29 | — | — | US | claimed |
| WO-2007026312-A1 | 1,3-DIAMINOBENZENE DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2007-03-08 | — | — | WO | claimed |
| EP-1760072-A1 | 1,3-diaminobenzene derivatives and colorants comprising these compounds | Wella Aktiengesellschaft (DE) | 2007-03-07 | — | — | EP | claimed |
| US-20070067923-A1 | 1,3-Diaminobenzene derivatives and colorants comprising these compounds | PROCTER & GAMBLE COMPANY, THE | 2007-03-29 | — | — | US | disclosed |
| WO-2007026312-A1 | 1,3-DIAMINOBENZENE DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2007-03-08 | — | — | WO | disclosed |
| EP-1760072-A1 | 1,3-diaminobenzene derivatives and colorants comprising these compounds | Wella Aktiengesellschaft (DE) | 2007-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070067923-A1 | 1,3-Diaminobenzene derivatives and colorants comprising these compounds | KRT18, DSP, DSG1 | KCNJ5 3931/4885KCNJ3 3913/4885PTGS1 979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.