Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | TYK2 | P29597 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5162952 | 0.85 | CYP1A2 (0.54) | SMN1; SMN2MAPTHDAC3HDAC4HDAC1 | |
| Ammonia Solution, Strong SCHEMBL5309981 | 0.84 | CYP1A2 (0.53) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5164480 | 0.84 | CYP1A1 (0.45) | RAB9AANO1BCHECA1CA2 | |
| SCHEMBL5162562 | 0.83 | ALDH1A1 (0.56) | RAB9ASMN1; SMN2NPC1POLBHDAC3 | |
| SCHEMBL5161551 | 0.82 | GAA (0.55) | SMN1; SMN2CA1CA2POLBMAPT | |
| SCHEMBL5164381 | 0.82 | POLB (0.53) | RAB9ASMN1; SMN2POLBMAPTHDAC3 | |
| SCHEMBL5163733 | 0.82 | KMT2A (0.53) | RAB9ASMN1; SMN2NPC1CA1CA2 | |
| SCHEMBL5161594 | 0.82 | KMT2A (0.55) | RAB9ASMN1; SMN2NPC1CA1CA2 | |
| SCHEMBL5162065 | 0.82 | KCNJ5 (0.56) | ANO1MAPT | |
| SCHEMBL5162110 | 0.81 | GAA (0.43) | RAB9ASMN1; SMN2ANO1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070067923-A1 | 1,3-Diaminobenzene derivatives and colorants comprising these compounds | PROCTER & GAMBLE COMPANY, THE | 2007-03-29 | — | — | US | claimed |
| WO-2007026312-A1 | 1,3-DIAMINOBENZENE DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2007-03-08 | — | — | WO | claimed |
| EP-1760072-A1 | 1,3-diaminobenzene derivatives and colorants comprising these compounds | Wella Aktiengesellschaft (DE) | 2007-03-07 | — | — | EP | claimed |
| US-20070067923-A1 | 1,3-Diaminobenzene derivatives and colorants comprising these compounds | PROCTER & GAMBLE COMPANY, THE | 2007-03-29 | — | — | US | disclosed |
| WO-2007026312-A1 | 1,3-DIAMINOBENZENE DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2007-03-08 | — | — | WO | disclosed |
| EP-1760072-A1 | 1,3-diaminobenzene derivatives and colorants comprising these compounds | Wella Aktiengesellschaft (DE) | 2007-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070067923-A1 | 1,3-Diaminobenzene derivatives and colorants comprising these compounds | KRT18, DSP, DSG1 | JAK2 1574/4885TYK2 2345/4885RAB9A 4739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.