Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 9/20 | 0.51 |
| ▸ | ITGA4 | P13612 | 9/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5160840 | 0.94 | ITGB1 (0.52) | ITGB1ITGA4KDM1AS1PR2MEN1 | |
| SCHEMBL5162870 | 0.89 | ITGB1 (0.44) | ITGB1ITGA4KDM1AS1PR2MEN1 | |
| SCHEMBL14371718 | 0.89 | ITGA4 (0.58) | ITGB1ITGA4KDM1AS1PR2MEN1 | |
| SCHEMBL14371700 | 0.89 | ITGA4 (0.58) | ITGB1ITGA4KDM1AS1PR2MEN1 | |
| SCHEMBL14371742 | 0.89 | ITGA4 (0.52) | ITGB1ITGA4KDM1AS1PR2MEN1 | |
| SCHEMBL14371708 | 0.89 | ITGA4 (0.58) | ITGB1ITGA4S1PR2 | |
| SCHEMBL14371750 | 0.88 | ITGA4 (0.49) | ITGB1ITGA4KDM1AS1PR2MEN1 | |
| SCHEMBL5158921 | 0.88 | ITGA4 (0.60) | ITGB1ITGA4KDM1AMEN1KMT2A | |
| SCHEMBL5161273 | 0.88 | ITGB1 (0.48) | ITGB1ITGA4KDM1AS1PR2MEN1 | |
| SCHEMBL5161277 | 0.88 | ITGA4 (0.52) | ITGB1ITGA4KDM1AS1PR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232601-A1 | Vla-4 Inhibitor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-10-04 | — | — | US | disclosed |
| US-20070232601-A1 | Vla-4 Inhibitor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-10-04 | — | — | US | disclosed |
| US-20070232601-A1 | Vla-4 Inhibitor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-10-04 | — | — | US | disclosed |
| EP-1757602-A1 | VLA-4 INHIBITOR | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-02-28 | — | — | EP | disclosed |
| EP-1757602-A1 | VLA-4 INHIBITOR | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232601-A1 | Vla-4 Inhibitor | VCAM1, ITGB4, ITGA4 | ITGB1 9/4885ITGA4 3/4885KDM1A 1794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.