Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4833079 | 0.76 | ALDH1A1 (0.41) | — | |
| SCHEMBL16746561 | 0.71 | CYP1A2 (0.43) | DOT1L | |
| SCHEMBL3787606 | 0.64 | MAPT (0.44) | DOT1L | |
| SCHEMBL21395985 | 0.64 | ESR1 (0.40) | DOT1L | |
| SCHEMBL28963581 | 0.64 | THRB (0.42) | — | |
| SCHEMBL3841471 | 0.63 | — | — | |
| SCHEMBL1138696 | 0.63 | TTR (0.36) | — | |
| SCHEMBL24747465 | 0.63 | ALDH1A1 (0.38) | — | |
| SCHEMBL2103990 | 0.63 | POLB (0.35) | DOT1L | |
| SCHEMBL21027096 | 0.62 | CYP1A2 (0.35) | DOT1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765359-A2 | ANTIBIOTICS CONTAINING BORINIC ACID COMPLEXES AND METHODS OF USE | Anacor Pharmaceuticals, Inc. (US) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006007384-A2 | ANTIBIOTICS CONTAINING BORINIC ACID COMPLEXES AND METHODS OF USE | ANACOR PHARMACEUTICALS, INC. (US) | 2006-01-19 | — | — | WO | disclosed |