SCHEMBL5162358

SCHEMBL5162358

CCOCCOC(O)CCS

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
TSHR P16473 1/20 0.34
THRB P10828 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7531391 0.86 TDP1 (0.41) TDP1
SCHEMBL11296774 0.85 ALDH1A1 (0.40) ALDH1A1TSHRTHRBTDP1
SCHEMBL13435130 0.82 TSHR (0.42) TSHRTHRBTDP1
SCHEMBL1679923 0.80
SCHEMBL1679971 0.78
SCHEMBL1679880 0.78
SCHEMBL2876197 0.78 ALDH1A1 (0.39) ALDH1A1TSHRTHRB
SCHEMBL10457072 0.76 ALDH1A1 (0.43) ALDH1A1TSHRTHRB
SCHEMBL1450274 0.76 ALDH1A1 (0.40) ALDH1A1TSHRTHRBTDP1
SCHEMBL1252225 0.76 ALDH1A1 (0.46) ALDH1A1TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070248554-A1 Hair Style Control Agent KAO CORPORATION (JP) 2007-10-25 US disclosed
EP-1752130-A1 HAIR STYLE CONTROL AGENT Kao Corporation (JP) 2007-02-14 EP disclosed
EP-0658338-B1 Straightening curly hair using compositions comprising keratin reducing substances and alcohols KAO CORP (JP) 2004-03-24 EP disclosed
US-20020146380-A1 For removal of body hairs and is decreased in odor KAO CORPORATION (JP) 2002-10-10 US disclosed
EP-0672405-B1 Hair treatment composition KAO CORP (JP) 2001-11-14 EP disclosed
US-6217855-B1 ELASTICITY KAO CORPORATION (JP) 2001-04-17 US disclosed
US-6156077-A Hair cosmetic composition comprising an oxyalkylenized xanthan gum KAO CORPORATION (JP) 2000-12-05 US disclosed
US-5958084-A CONSISTS OF AN OXIDATION DYE PRECURSOR, A COUPLER AND AN OXYALKYLENIZED XANTHANE GUM, AND A SALT OF INORGANIC ACID OR ORGANIC ACID KAO CORPORATION (JP) 1999-09-28 US disclosed
US-5665338-A KERATIN-REDUCING SUBSTANCE, NONIONIC AMPHIPHATIC COMPOUND KAO CORPORATION (JP) 1997-09-09 US disclosed
EP-0784970-A2 Hair cosmetic composition Kao Corporation (JP) 1997-07-23 EP disclosed
US-5609860-A Curly hair-straightening composition KAO CORPORATION (JP) 1997-03-11 US disclosed
EP-0672405-A1 Hair treatment composition KAO CORPORATION (JP) 1995-09-20 EP disclosed
EP-0658338-A1 Curly hair-straightening composition comprising keratin reducing substances and alcohols KAO CORPORATION (JP) 1995-06-21 EP disclosed
EP-0529437-A1 Hair treatment composition Kao Corporation (JP) 1993-03-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070248554-A1 Hair Style Control Agent KRT18, S100A4, S100A10 ALDH1A1 926/4885TSHR 1281/4885THRB 679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.