Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 8/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 8/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | CFD | P00746 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5161285 | 0.94 | ITGB1 (0.37) | ITGB1ITGA4HDAC1HDAC6BCHE | |
| SCHEMBL5163101 | 0.94 | ITGB1 (0.39) | ITGB1ITGA4CREBBPHDAC1HDAC6 | |
| SCHEMBL5161449 | 0.88 | ITGB1 (0.39) | ITGB1ITGA4HDAC1HDAC6CFD | |
| SCHEMBL14371622 | 0.86 | ITGB1 (0.48) | ITGB1ITGA4CREBBPBCHEACHE | |
| SCHEMBL5162597 | 0.86 | ITGB1 (0.48) | ITGB1ITGA4CREBBPBCHEACHE | |
| SCHEMBL5163092 | 0.84 | ITGB1 (0.50) | ITGB1ITGA4CFDACKR3 | |
| SCHEMBL14371621 | 0.84 | ITGB1 (0.50) | ITGB1ITGA4CFDACKR3 | |
| SCHEMBL5161273 | 0.80 | ITGB1 (0.48) | ITGB1ITGA4CFDKDM1AACKR3 | |
| SCHEMBL14371779 | 0.80 | ITGB1 (0.48) | ITGB1ITGA4CFDKDM1AACKR3 | |
| SCHEMBL14371778 | 0.78 | ITGB1 (0.49) | ITGB1ITGA4CFDKDM1AACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232601-A1 | Vla-4 Inhibitor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-10-04 | — | — | US | disclosed |
| EP-1757602-A1 | VLA-4 INHIBITOR | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232601-A1 | Vla-4 Inhibitor | VCAM1, ITGB4, ITGA4 | ITGB1 9/4885ITGA4 3/4885CREBBP 3270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.