SCHEMBL5162705

SCHEMBL5162705

O=C(CC(=O)C(F)(F)F)OCc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
MAPK1 P28482 1/20 0.58
CES1 P23141 4/20 0.55
LMNA P02545 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
KMT2A Q03164 3/20 0.49
SLC6A2 P23975 1/20 0.49
SLC6A3 Q01959 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
MEN1 O00255 2/20 0.48
FAAH O00519 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL294341 0.83 ALDH1A1 (0.73) ALDH1A1L3MBTL1MAPK1LMNASMN1; SMN2
SCHEMBL5249734 0.83 ALDH1A1 (0.58) ALDH1A1L3MBTL1MAPK1LMNASMN1; SMN2
SCHEMBL8069055 0.81 ALDH1A1 (0.70) ALDH1A1L3MBTL1MAPK1LMNASMN1; SMN2
SCHEMBL1931085 0.80 ALDH1A1 (0.54) ALDH1A1L3MBTL1MAPK1LMNASMN1; SMN2
SCHEMBL338280 0.80 ALDH1A1 (0.68) ALDH1A1L3MBTL1MAPK1LMNASMN1; SMN2
SCHEMBL1011103 0.80 ALDH1A1 (0.68) ALDH1A1L3MBTL1MAPK1LMNASMN1; SMN2
SCHEMBL12586386 0.79 ALDH1A1 (0.61) ALDH1A1L3MBTL1MAPK1CES1LMNA
SCHEMBL5751558 0.78 ALDH1A1 (0.66) ALDH1A1L3MBTL1MAPK1LMNASMN1; SMN2
SCHEMBL3296385 0.78 ALDH1A1 (0.57) ALDH1A1L3MBTL1MAPK1CES1LMNA
SCHEMBL27712861 0.78 ALDH1A1 (0.66) ALDH1A1L3MBTL1MAPK1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250234865-A1 Additive Composition for Antifouling Coatings Arxada, LLC 2025-07-24 US disclosed
EP-4402215-A1 ADDITIVE COMPOSITION FOR ANTIFOULING COATINGS Arxada, LLC (US) 2024-07-24 EP disclosed
WO-2023064524-A1 ADDITIVE COMPOSITION FOR ANTIFOULING COATINGS Arxada, LLC (US) 2023-04-20 WO disclosed
EP-3707143-B9 NEW ANALOGS AS ANDROGEN RECEPTOR AND GLUCOCORTICOID RECEPTOR MODULATORS ONCOSTELLAE S L (ES) 2023-04-12 EP disclosed
US-20230019988-A1 Compositions for Antifouling Protection Arxada Switzerland AG (CH) 2023-01-19 US disclosed
EP-3707143-B1 NEW ANALOGS AS ANDROGEN RECEPTOR AND GLUCOCORTICOID RECEPTOR MODULATORS ONCOSTELLAE S L (ES) 2022-12-28 EP disclosed
US-11453660-B2 Androgen receptor and glucocorticoid receptor modulators ONCOSTELLAE, S.L. 2022-09-27 US disclosed
CN-114026181-A Composition for antifouling protection 阿尔萨达股份公司 2022-02-08 CN disclosed
EP-3856852-A1 COMPOSITIONS FOR ANTIFOULING PROTECTION Lonza Solutions AG (CH) 2021-08-04 EP disclosed
WO-2021113564-A1 COMPOSITIONS FOR ANTIFOULING PROTECTION LONZA SOLUTIONS AG (CH) 2021-06-10 WO disclosed
US-6893861-B1 Method for producing trifluoro-3(r)-hydroxybutyric acid derivatives LONZA AG (CH) 2005-05-17 US disclosed
US-20020147222-A1 Dihydropyridine derivatives AJINOMOTO CO. INC (JP) 2002-10-10 US disclosed
US-6380134-B1 USED FOR CONTROLLING WEEDS SYNGENTA CROP PROTECTION, INC. 2002-04-30 US disclosed
EP-1191021-A1 DIHYDROPYRIDINE DERIVATIVE Ajinomoto Co., Inc. (JP) 2002-03-27 EP disclosed
EP-1084117-A2 NOVEL HERBICIDES Novartis AG (CH) 2001-03-21 EP disclosed
EP-1054974-A1 METHOD FOR PRODUCING TRIFLUORO-3(R)-HYDROXYBUTYRIC ACID DERIVATIVES Lonza AG (CH) 2000-11-29 EP disclosed
WO-1999052892-A2 NOVEL HERBICIDES NOVARTIS AG (CH) 1999-10-21 WO disclosed
WO-1999042590-A1 METHOD FOR PRODUCING TRIFLUORO-3(R)-HYDROXYBUTYRIC ACID DERIVATIVES LONZA AG (CH) 1999-08-26 WO disclosed
US-4396626-A (1-METHYL-4-TRIFLUOROMETHYL-5-ARYLCARBONYL-4-PYRRYL)ALKANOIC ACID OR DERIVATIVE; ANALGESIC, ANTIINFLAMMATORY BEECHAM GROUP LIMITED (GB) 1983-08-02 US disclosed
EP-0049999-A2 Cyclic compounds and their preparation and use BEECHAM GROUP PLC (GB) 1982-04-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250234865-A1 Additive Composition for Antifouling Coatings PSPH, PHOSPHO1, CFD ALDH1A1 1165/4885L3MBTL1 2184/4885MAPK1 4052/4885
US-11453660-B2 Androgen receptor and glucocorticoid receptor modulators AR, NR5A1, NR3C1 ALDH1A1 1496/4885L3MBTL1 4731/4885MAPK1 963/4885
US-20020147222-A1 Dihydropyridine derivatives CACNA1B, CACNA1D, CACNA1C ALDH1A1 2039/4885L3MBTL1 3370/4885MAPK1 2345/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.