Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | SLC13A5 | Q86YT5 | 3/20 | 0.31 |
| ▸ | SLC13A2 | Q13183 | 1/20 | 0.31 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | CPT2 | P23786 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HMGCR | P04035 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5162755 | 0.71 | FFAR1 (0.34) | CYP2D6TSHRCYP2C19HIF1ASLC13A5 | |
| SCHEMBL3930895 | 0.71 | ALDH1A1 (0.48) | CYP2D6TSHRCYP2C19HIF1AFFAR1 | |
| SCHEMBL27323864 | 0.70 | ALDH1A1 (0.39) | CYP2D6TSHRCYP2C19HIF1AFFAR1 | |
| SCHEMBL11211995 | 0.68 | CYP2D6 (0.44) | CYP2D6TSHRCYP2C19HIF1AFFAR1 | |
| SCHEMBL6567151 | 0.67 | FFAR1 (0.32) | CYP2D6TSHRCYP2C19HIF1AFFAR1 | |
| SCHEMBL19457979 | 0.67 | FFAR1 (0.31) | FFAR1CPT2TDP1 | |
| SCHEMBL28574187 | 0.67 | LMNA (0.30) | — | |
| Acetic Acid SCHEMBL28071403 | 0.66 | — | — | |
| SCHEMBL909260 | 0.65 | TSHR (0.41) | TSHRTDP1ALDH1A1 | |
| SCHEMBL28777934 | 0.65 | ALDH1A1 (0.42) | CYP2D6TSHRCYP2C19HIF1AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8343474-B2 | Substituted organopolysiloxanes and uses thereof | PHOSPHONICS LTD. (GB) | 2013-01-01 | — | — | US | disclosed |
| EP-1987082-B1 | SUBTITUTED ORGANOPOLYSILOXANES AND USE THEREOF | PHOSPHONICS LTD (GB) | 2012-05-02 | — | — | EP | disclosed |
| US-20090220449-A1 | SUBSTITUTED ORGANOPOLYSILOXANES AND USES THEREOF | PHOSPHONICS LTD (GB) | 2009-09-03 | — | — | US | disclosed |
| EP-1987082-A1 | SUBTITUTED ORGANOPOLYSILOXANES AND USE THEREOF | Phosphonics Ltd. (GB) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007090676-A1 | SUBTITUTED ORGANOPOLYSILOXANES AND USE THEREOF | PHOSPHONICS LTD (GB) | 2007-08-16 | — | — | WO | disclosed |