SCHEMBL516287

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10196155	0.90	MAOA (0.39)	MAOBMAOAHTR2ASLC6A4KCNH2
	SCHEMBL10187648	0.88	MEN1 (0.36)	MAOBMAOAHTR2ASLC6A4KCNH2
	SCHEMBL10195108	0.83	MAOA (0.41)	MAOBMAOAHTR2ASLC6A4KCNH2
	SCHEMBL10187650	0.83	PDE4B (0.34)	HTR2ASLC6A4KCNH2ALDH1A1LMNA
	SCHEMBL19070665	0.82	MAOA (0.41)	MAOBMAOAELANEALDH1A1LMNA
	SCHEMBL10196025	0.79	HSP90AA1 (0.41)	HTR2ASLC6A4KCNH2HIF1A
	SCHEMBL10196150	0.78	HTR2A (0.42)	HTR2ASLC6A4KCNH2LMNAHIF1A
	SCHEMBL10196154	0.78	LTB4R (0.37)	MAOBMAOAHSD17B1MEN1KMT2A
	SCHEMBL10196167	0.78	MAOB (0.42)	MAOBMAOAALDH1A1HSD17B1MEN1
	SCHEMBL10196044	0.77	MAOA (0.39)	MAOBMAOAELANEALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.