SCHEMBL5162875

SCHEMBL5162875

COc1c(O)cc(O)c2c(=O)cc(-c3ccccc3O)oc12

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 1/20 0.74
GABRD O14764 1/20 0.74
KDM1A O60341 1/20 0.74
CCNT1 O60563 1/20 0.74
PKM P14618 1/20 0.74
GABRA1 P14867 1/20 0.74
GABRB1 P18505 1/20 0.74
GABRG2 P18507 1/20 0.74
CCNA2 P20248 1/20 0.74
CCNC P24863 1/20 0.74
CDK2 P24941 1/20 0.74
GABRB3 P28472 1/20 0.74
GABRA5 P31644 1/20 0.74
GABRA3 P34903 1/20 0.74
PTGS2 P35354 1/20 0.74
GABRA2 P47869 1/20 0.74
GABRB2 P47870 1/20 0.74
GABRA4 P48169 1/20 0.74
CDK8 P49336 1/20 0.74
CDK7 P50613 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29927214 1.00 GABRP (0.74) GABRPGABRDKDM1ACCNT1PKM
SCHEMBL29411332 0.90 ACHE (0.76) GABRPGABRDKDM1ACCNT1PKM
SCHEMBL6069761 0.90 ACHE (0.76) GABRPGABRDKDM1ACCNT1PKM
SCHEMBL5163180 0.90 GABRP (0.71) GABRPGABRDKDM1ACCNT1PKM
SCHEMBL4625384 0.86 ALDH1A1 (0.64) GABRPGABRDKDM1ACCNT1PKM
SCHEMBL28661728 0.86 ALDH1A1 (0.75) GABRPGABRDKDM1ACCNT1PKM
Wogonin SCHEMBL139083 0.85 GABRP (1.00) GABRPGABRDKDM1ACCNT1PKM
Wogonin SCHEMBL29632729 0.85 GABRP (1.00) GABRPGABRDKDM1ACCNT1PKM
SCHEMBL16894649 0.85 CYP1A1 (0.65) GABRPGABRDKDM1ACCNT1PKM
SCHEMBL27775457 0.84 ALDH1A1 (0.65) GABRPGABRDKDM1ACCNT1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0859557-B1 FOODS AND BEVERAGES CONTAINING ANTHOCYANINS STABILIZED BY PLANT EXTRACTS NATUREX INC (US) 2007-03-21 EP claimed
EP-0332478-B1 LIPOSOMES CONTAINING SCUTELLARIA EXTRACTS LVMH RECH (FR) 1992-03-25 EP claimed
WO-1989008447-A1 LIPOSOMES CONTAINING SCUTELLARIA EXTRACTS LVMH RECHERCHE (FR) 1989-09-21 WO claimed
EP-0332478-A1 Liposomes containing Scutellaria extracts LVMH RECHERCHE (FR) 1989-09-13 EP claimed
CN-102516218-A Method for preparing herba scutellariae barbatae with high purity SUZHOU BAOZETANG MEDICAL TECH 2012-06-27 CN disclosed
US-5643598-A LIPIDS FOR TREATMENT OF SKIN DISORDERS AS ANTIALLERGENS, ANTIINFLAMMATORY AGENTS OR ANTIAGING COMPOUNDS LVMH RECHERCHE (FR) 1997-07-01 US disclosed
US-5443839-A Antiinflammatory, antiallergic and antiaging activity LVMH RECHERCHE (FR) 1995-08-22 US disclosed
EP-0332478-B1 LIPOSOMES CONTAINING SCUTELLARIA EXTRACTS LVMH RECH (FR) 1992-03-25 EP disclosed
WO-1989008447-A1 LIPOSOMES CONTAINING SCUTELLARIA EXTRACTS LVMH RECHERCHE (FR) 1989-09-21 WO disclosed
EP-0332478-A1 Liposomes containing Scutellaria extracts LVMH RECHERCHE (FR) 1989-09-13 EP disclosed