Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 4/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | PPIP5K2 | O43314 | 1/20 | 0.33 |
| ▸ | LAP3 | P28838 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1091578 | 1.00 | FDPS (0.42) | FDPSMMP1MMP2MMP3MMP8 | |
| SCHEMBL21489150 | 0.94 | FDPS (0.42) | FDPSMMP1MMP2MMP3MMP8 | |
| Phosphoric Acid SCHEMBL28801115 | 0.87 | FDPS (0.46) | FDPSMMP1MMP2MMP3MMP8 | |
| Phosphoric Acid SCHEMBL21359160 | 0.87 | FDPS (0.46) | FDPSMMP1MMP2MMP3MMP8 | |
| Phosphoric Acid SCHEMBL16093844 | 0.87 | FDPS (0.46) | FDPSMMP1MMP2MMP3MMP8 | |
| Phosphoric Acid SCHEMBL9359318 | 0.87 | FDPS (0.46) | FDPSMMP1MMP2MMP3MMP8 | |
| Phosphoric Acid SCHEMBL1019439 | 0.87 | FDPS (0.46) | FDPSMMP1MMP2MMP3MMP8 | |
| Phosphoric Acid SCHEMBL192006 | 0.87 | FDPS (0.46) | FDPSMMP1MMP2MMP3MMP8 | |
| Phosphoric Acid SCHEMBL192007 | 0.87 | FDPS (0.46) | FDPSMMP1MMP2MMP3MMP8 | |
| Phosphoric Acid SCHEMBL23751823 | 0.84 | FDPS (0.43) | FDPSMMP1MMP2MMP3MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11066436-B2 | 5′-phosphorothiolate mRNA 5′-end (cap) analogs, mRNA comprising the same, method of obtaining and uses thereof | UNIWERSYTET WARSZAWSKI (PL) | 2021-07-20 | — | — | US | disclosed |
| EP-3408276-B1 | 5'-PHOSPHOROTHIOLATE MRNA 5'-END (CAP) ANALOGS, MRNA COMPRISING THE SAME, METHOD OF OBTAINING AND USES THEREOF | UNIV WARSZAWSKI (PL) | 2021-04-07 | — | — | EP | disclosed |
| US-20190300563-A1 | 5'-Phosphorothiolate mRNA 5'-end (cap) Analogs, mRNA Comprising the Same, Method of Obtaining and Uses Thereof | UNIWERSYTET WARSZAWSKI (PL) | 2019-10-03 | — | — | US | disclosed |
| EP-3408276-A1 | 5'-PHOSPHOROTHIOLATE MRNA 5'-END (CAP) ANALOGS, MRNA COMPRISING THE SAME, METHOD OF OBTAINING AND USES THEREOF | Uniwersytet Warszawski (PL) | 2018-12-05 | — | — | EP | disclosed |
| WO-2017130151-A1 | 5'-PHOSPHOROTHIOLATE MRNA 5'-END (CAP) ANALOGS, MRNA COMPRISING THE SAME, METHOD OF OBTAINING AND USES THEREOF | UNIWERSYTET WARSZAWSKI (PL) | 2017-08-03 | — | — | WO | disclosed |
| EP-1765844-A2 | PURINE NUCLEOTIDE DERIVATIVES | Lauras AS (NO) | 2007-03-28 | — | — | EP | disclosed |
| WO-2005123755-A2 | PURINE NUCLEOTIDE DERIVATIVES | LAURAS AS (NO) | 2005-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11066436-B2 | 5′-phosphorothiolate mRNA 5′-end (cap) analogs, mRNA comprising the same, method of obtaining and uses thereof | RNGTT, RNMT, MTAP | FDPS 682/4885MMP1 2496/4885MMP2 1936/4885 |
| US-20190300563-A1 | 5'-Phosphorothiolate mRNA 5'-end (cap) Analogs, mRNA Comprising the Same, Method of Obtaining and Uses Thereof | RNGTT, RNMT, MTAP | FDPS 682/4885MMP1 2470/4885MMP2 1925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.