Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NDUFS8 | O00217 | 1/20 | 0.47 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.47 |
| ▸ | NDUFAB1 | O14561 | 1/20 | 0.47 |
| ▸ | NDUFA1 | O15239 | 1/20 | 0.47 |
| ▸ | NDUFS4 | O43181 | 1/20 | 0.47 |
| ▸ | NDUFB5 | O43674 | 1/20 | 0.47 |
| ▸ | NDUFB3 | O43676 | 1/20 | 0.47 |
| ▸ | NDUFC1 | O43677 | 1/20 | 0.47 |
| ▸ | NDUFA2 | O43678 | 1/20 | 0.47 |
| ▸ | NDUFS5 | O43920 | 1/20 | 0.47 |
| ▸ | NDUFS7 | O75251 | 1/20 | 0.47 |
| ▸ | NDUFS2 | O75306 | 1/20 | 0.47 |
| ▸ | NDUFS6 | O75380 | 1/20 | 0.47 |
| ▸ | NDUFB1 | O75438 | 1/20 | 0.47 |
| ▸ | NDUFS3 | O75489 | 1/20 | 0.47 |
| ▸ | NDUFB6 | O95139 | 1/20 | 0.47 |
| ▸ | NDUFA3 | O95167 | 1/20 | 0.47 |
| ▸ | NDUFB4 | O95168 | 1/20 | 0.47 |
| ▸ | NDUFB8 | O95169 | 1/20 | 0.47 |
| ▸ | NDUFB2 | O95178 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8036010 | 0.84 | KDM4E (0.53) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| SCHEMBL11570459 | 0.81 | NDUFS8 (0.46) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| SCHEMBL10269260 | 0.80 | MAPT (0.49) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| SCHEMBL31590280 | 0.79 | PPARD (0.61) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| SCHEMBL4114408 | 0.79 | KDM4E (0.49) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| Etrogol SCHEMBL18265493 | 0.79 | NDUFS8 (0.50) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| SCHEMBL17748389 | 0.78 | TRPA1 (0.44) | KDM4EALDH1A1HTTMAPTHPGD | |
| SCHEMBL10805062 | 0.78 | NDUFS8 (0.53) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| SCHEMBL5164271 | 0.78 | KDM4E (0.47) | KDM4EALDH1A1MTNR1AMAPTHPGD | |
| SCHEMBL25806392 | 0.77 | TAAR1 (0.52) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1768945-A1 | SUBSTITUTED HYDROXYACETOPHENON DERIVATIVES | Riemser Arzneimittel AG (DE) | 2007-04-04 | — | — | EP | claimed |
| WO-2006003010-A1 | SUBSTITUTED HYDROXYACETOPHENON DERIVATIVES | RIEMSER ARZNEIMITTEL AG (DE) | 2006-01-12 | — | — | WO | claimed |
| EP-1768945-A1 | SUBSTITUTED HYDROXYACETOPHENON DERIVATIVES | Riemser Arzneimittel AG (DE) | 2007-04-04 | — | — | EP | disclosed |
| WO-2006003010-A1 | SUBSTITUTED HYDROXYACETOPHENON DERIVATIVES | RIEMSER ARZNEIMITTEL AG (DE) | 2006-01-12 | — | — | WO | disclosed |