Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16166393 | 0.86 | ALOX5 (0.43) | KDM4EALDH1A1MTNR1AALOX5HPGD | |
| SCHEMBL3897112 | 0.80 | L3MBTL1 (0.43) | KDM4EALDH1A1MTNR1AHPGDMAPT | |
| SCHEMBL11583616 | 0.79 | ALOX5 (0.52) | KDM4EALDH1A1MTNR1AALOX5HPGD | |
| SCHEMBL5163415 | 0.78 | NDUFS8 (0.47) | KDM4EALDH1A1MTNR1AHPGDMAPT | |
| SCHEMBL3901893 | 0.77 | ALOX5 (0.58) | KDM4EALDH1A1MTNR1AALOX5HPGD | |
| SCHEMBL1682636 | 0.76 | KDM4E (0.49) | KDM4EALDH1A1MAPTMEN1LMNA | |
| SCHEMBL6653306 | 0.76 | MAPT (0.60) | KDM4EALDH1A1MTNR1AALOX5HPGD | |
| SCHEMBL5166899 | 0.75 | TRPA1 (0.44) | KDM4EALDH1A1MTNR1AALOX5HPGD | |
| SCHEMBL8889572 | 0.75 | MTNR1A (0.36) | KDM4EALDH1A1MTNR1AHPGDMAPT | |
| SCHEMBL7179024 | 0.73 | ALDH1A1 (0.61) | KDM4EALDH1A1MTNR1AALOX5HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1768945-A1 | SUBSTITUTED HYDROXYACETOPHENON DERIVATIVES | Riemser Arzneimittel AG (DE) | 2007-04-04 | — | — | EP | disclosed |
| WO-2006003010-A1 | SUBSTITUTED HYDROXYACETOPHENON DERIVATIVES | RIEMSER ARZNEIMITTEL AG (DE) | 2006-01-12 | — | — | WO | disclosed |