SCHEMBL5163603

SCHEMBL5163603

CCC(CC)CCCOc1cccc(-c2nc(-c3ccc(OC)cc3)nc(-c3cccc(OCCCC(CC)CC)c3O)n2)c1O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.40
MEN1 O00255 5/20 0.40
NPC1 O15118 2/20 0.40
MAPT P10636 9/20 0.39
HIF1A Q16665 3/20 0.39
GAA P10253 2/20 0.39
GBA1 P04062 1/20 0.39
GLA P06280 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
TP53 P04637 2/20 0.38
CLK4 Q9HAZ1 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
HPGD P15428 3/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KDM4E B2RXH2 4/20 0.35
ALDH1A1 P00352 3/20 0.35
CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4959016 0.93 MAPT (0.36) KMT2AMEN1NPC1MAPTHIF1A
SCHEMBL5550291 0.89 MEN1 (0.41) KMT2AMEN1MAPTHIF1AGAA
SCHEMBL4554162 0.89 TDP1 (0.41) KMT2AMEN1NPC1MAPTHIF1A
SCHEMBL5546832 0.86 TRPV1 (0.36) KMT2AMEN1NPC1MAPTHIF1A
SCHEMBL5550275 0.83 CYP3A4 (0.36) KMT2AMEN1MAPTHIF1AGAA
SCHEMBL7093852 0.82 NPC1 (0.40) KMT2AMEN1NPC1MAPTTDP1
SCHEMBL5550266 0.81 CNR2 (0.41) KMT2AMEN1MAPTHIF1AGAA
SCHEMBL5163597 0.81 MAPT (0.44) KMT2AMEN1NPC1MAPTGAA
SCHEMBL12216378 0.80 MEN1 (0.56) KMT2AMEN1NPC1MAPTHIF1A
SCHEMBL580178 0.79 MEN1 (0.39) KMT2AMEN1NPC1MAPTHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070202233-A1 Plant Cell-Derived Pectin MITSUI CHEMICALS, INC. (JP) 2007-08-30 US disclosed
EP-1333803-B1 USE OF CARBOHYDRATE FOR ENHANCING THE SKIN BARRIER FUNCTION OREAL (FR) 2007-04-25 EP disclosed
EP-1333804-B1 COMPOSITIONS COMPRISING BETA-GALACTOSIDASE, N-ACETYL-GLUCOSAMINIDASE AND N-ACETYL-GALACTOSAMINIDASE, SAID COMPOSITIONS NOT COMPRISING PROTEASE OREAL (FR) 2007-03-21 EP disclosed
US-20060165632-A1 Use of carbohydrates to improve skin barrier function SOCIETE L'OREAL S.A. (FR) 2006-07-27 US disclosed
US-20050244360-A1 Cosmetic composition for greasy skin care, containing a carboxylic fatty acid or a derivative thereof L'OREAL (FR) 2005-11-03 US disclosed
EP-1581180-A1 COSMETIC COMPOSITION FOR GREASY SKIN CARE, CONTAINING A CARBOXYLIC FATTY ACID OR A DERIVATIVE THEREOF L'OREAL (FR) 2005-10-05 EP disclosed
WO-2004069219-A1 COSMETIC COMPOSITION FOR GREASY SKIN CARE, CONTAINING A CARBOXYLIC FATTY ACID OR A DERIVATIVE THEREOF L'OREAL (FR) 2004-08-19 WO disclosed
US-20040115187-A1 Compositions comprising at least one glyconsidase, said compositions containing no proteases SOCIETE L'OREAL S.A. (FR) 2004-06-17 US disclosed
US-20040062739-A1 Use of carbohydrates to improve skin barrier function SOCIETE L'OREAL S.A. (FR) 2004-04-01 US disclosed
EP-1175888-A2 Topical compositions comprising glycosylated hydroxystilbenes and their uses L'OREAL (FR) 2002-01-30 EP disclosed