SCHEMBL4554162

SCHEMBL4554162

CCCCC(CC)COc1cccc(-c2nc(-c3ccc(OC)cc3)nc(-c3cccc(OCC(CC)CCCC)c3O)n2)c1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.41
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
NPC1 O15118 1/20 0.40
MAPT P10636 5/20 0.40
HIF1A Q16665 3/20 0.40
GAA P10253 2/20 0.40
GBA1 P04062 1/20 0.40
GLA P06280 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
TP53 P04637 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP1A2 P05177 1/20 0.36
HPGD P15428 1/20 0.36
CYP2C19 P33261 1/20 0.36
HTT P42858 1/20 0.36
CA2 P00918 1/20 0.35
CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5163603 0.89 KMT2A (0.40) TDP1MEN1KMT2ANPC1MAPT
SCHEMBL28678998 0.87 LMNA (0.38) TDP1MEN1KMT2ANPC1MAPT
SCHEMBL7057519 0.83 LMNA (0.41) TDP1MEN1KMT2ANPC1MAPT
Bemotrizinol SCHEMBL29360093 0.82 TDP1 (0.43) TDP1MEN1KMT2ANPC1MAPT
Bemotrizinol SCHEMBL77320 0.82 TDP1 (0.43) TDP1MEN1KMT2ANPC1MAPT
SCHEMBL10195000 0.82 TDP1 (0.43) TDP1MEN1KMT2ANPC1MAPT
Bemotrizinol SCHEMBL29350308 0.82 TDP1 (0.43) TDP1MEN1KMT2ANPC1MAPT
SCHEMBL12877715 0.82 TDP1 (0.39) TDP1MEN1KMT2ANPC1MAPT
Bemotrizinol SCHEMBL26987980 0.82 TDP1 (0.39) TDP1MEN1KMT2ANPC1MAPT
SCHEMBL4959016 0.82 MAPT (0.36) TDP1MEN1KMT2ANPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2946779-A1 COSMETIC AND PHARMACEUTICAL APPLICATIONS OF N-ACETYLHYDROXYPROLINE Beiersdorf AG (DE) 2015-11-25 EP claimed
EP-2932958-A1 COSMETIC AND PHARMACEUTICAL APPLICATIONS OF N-ACETYLHYDROXYPROLINE Beiersdorf AG (DE) 2015-10-21 EP claimed
EP-2124934-B1 COSMETIC AND PHARMACEUTICAL APPLICATIONS OF N-ACETYLHYDROXYPROLINE BEIERSDORF AG (DE) 2015-04-08 EP claimed
EP-2124934-A2 COSMETIC AND PHARMACEUTICAL APPLICATIONS OF N-ACETYLHYDROXYPROLINE Beiersdorf AG (DE) 2009-12-02 EP claimed
EP-2117536-A2 COSMETIC AND PHARMACEUTICAL APPLICATIONS OF N-ACYLATED AMINO ACIDS AND STRUCTURALLY RELATED COMPOUNDS Beiersdorf AG (DE) 2009-11-18 EP claimed
WO-2008101692-A2 COSMETIC AND PHARMACEUTICAL APPLICATIONS OF N-ACETYLHYDROXYPROLINE BEIERSDORF AG (DE) 2008-08-28 WO claimed
WO-2008101693-A2 COSMETIC AND PHARMACEUTICAL APPLICATIONS OF N-ACYLATED AMINO ACIDS AND STRUCTURALLY RELATED COMPOUNDS BEIERSDORF AG (DE) 2008-08-28 WO claimed
EP-1524960-A2 COSMETIC OR DERMATOLOGICAL PREPARATION FOR PROTECTING PHOTOLABILE ACTIVE INGREDIENTS Beiersdorf AG (DE) 2005-04-27 EP claimed
WO-2004004670-A2 COSMETIC OR DERMATOLOGICAL PREPARATION FOR PROTECTING PHOTOLABILE ACTIVE INGREDIENTS BEIERSDORF AG (DE) 2004-01-15 WO claimed
CN-109475490-B Hair care composition containing wheat bran extract 西姆莱斯股份公司 2021-11-30 CN disclosed
EP-2946779-A1 COSMETIC AND PHARMACEUTICAL APPLICATIONS OF N-ACETYLHYDROXYPROLINE Beiersdorf AG (DE) 2015-11-25 EP disclosed
EP-2932958-A1 COSMETIC AND PHARMACEUTICAL APPLICATIONS OF N-ACETYLHYDROXYPROLINE Beiersdorf AG (DE) 2015-10-21 EP disclosed
EP-2124934-B1 COSMETIC AND PHARMACEUTICAL APPLICATIONS OF N-ACETYLHYDROXYPROLINE BEIERSDORF AG (DE) 2015-04-08 EP disclosed
US-20130236397-A1 HAIR SETTING COMPOSITIONS BASED ON T-BUTYL ACRYLATE AND HYDROXYALKYL METHACRYLATE BASF SE (DE) 2013-09-12 US disclosed
US-6869597-B2 Cosmetic care or makeup composition for a keratin material comprising at least one photoprotective agent and at least one ester comprising an aromatic group L'OREAL S.A. (FR) 2005-03-22 US disclosed
US-6685924-B2 COMPLEX OF INORGANIC PIGMENT AND ACTIVE MATERIAL MERCK PATENT GMBH (DE) 2004-02-03 US disclosed
WO-2004004670-A2 COSMETIC OR DERMATOLOGICAL PREPARATION FOR PROTECTING PHOTOLABILE ACTIVE INGREDIENTS BEIERSDORF AG (DE) 2004-01-15 WO disclosed
US-20030082117-A1 Genus leontopodium plant extract and compositions containing same L'OREAL (FR) 2003-05-01 US disclosed
US-20030077234-A1 Cosmetic care or makeup composition for a keratin material comprising at least one photoprotective agent and at least one ester comprising an aromatic group L'OREAL. 2003-04-24 US disclosed
US-20020150600-A1 Conjugate, its preparation and use MERCK PATENT GMBH (DE) 2002-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020150600-A1 Conjugate, its preparation and use TYR, MPO, DDT TDP1 1844/4885MEN1 551/4885KMT2A 638/4885
US-20130236397-A1 HAIR SETTING COMPOSITIONS BASED ON T-BUTYL ACRYLATE AND HYDROXYALKYL METHACRYLATE MTR, ABHD10, ACR TDP1 2931/4885MEN1 1551/4885KMT2A 2102/4885
US-20030077234-A1 Cosmetic care or makeup composition for a keratin material comprising at least one photoprotective agent and at least one ester comprising an aromatic group KRT18, CUTA, TYR TDP1 858/4885MEN1 2409/4885KMT2A 1964/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.