Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7057519 | 0.89 | LMNA (0.41) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL5163597 | 0.84 | MAPT (0.44) | NPC1MEN1KMT2AMAPTHPGD | |
| SCHEMBL5163603 | 0.82 | KMT2A (0.40) | NPC1MEN1KMT2AMAPTATM | |
| SCHEMBL16746693 | 0.80 | NPC1 (0.57) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL15909996 | 0.80 | NPC1 (0.57) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL6512448 | 0.80 | NPC1 (0.57) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL4959013 | 0.80 | HTT (0.43) | NPC1MEN1KMT2AMAPTHPGD | |
| SCHEMBL5550293 | 0.79 | GAA (0.42) | MEN1KMT2AMAPTHPGDTSHR | |
| SCHEMBL28678998 | 0.79 | LMNA (0.38) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL29364346 | 0.77 | ALOX15 (0.62) | NPC1RAB9AMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1333804-A2 | COMPOSITIONS COMPRISING AT LEAST A GLYCOSIDASE, SAID COMPOSITIONS NOT COMPRISING PROTEASE | L'OREAL S.A. (FR) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002038122-A2 | COMPOSITIONS COMPRISING AT LEAST A GLYCOSIDASE, SAID COMPOSITIONS NOT COMPRISING PROTEASE | L'OREAL S.A (FR) | 2002-05-16 | — | — | WO | disclosed |