Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 14/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9715679 | 0.82 | AR (0.46) | ARTSHRALDH1A1HTR2AHTR2C | |
| SCHEMBL1343673 | 0.80 | HSD17B10 (0.39) | TSHRALDH1A1MEN1TP53CYP3A4 | |
| SCHEMBL13106347 | 0.80 | AR (0.51) | ARTSHRALDH1A1 | |
| SCHEMBL29863815 | 0.80 | AR (0.51) | ARTSHRALDH1A1 | |
| SCHEMBL17570552 | 0.79 | TSHR (0.46) | ARTSHRALDH1A1MEN1TP53 | |
| SCHEMBL10941730 | 0.79 | TRPV4 (0.45) | ARALDH1A1HTR2AHTR2CHTR2B | |
| SCHEMBL31038739 | 0.79 | TRPV4 (0.45) | ARALDH1A1HTR2AHTR2CHTR2B | |
| SCHEMBL29398131 | 0.77 | TSHR (0.44) | ARTSHRALDH1A1MEN1MAPT | |
| SCHEMBL8852021 | 0.77 | TSHR (0.44) | ARTSHRALDH1A1MEN1MAPT | |
| SCHEMBL23846799 | 0.77 | L3MBTL1 (0.50) | TSHRALDH1A1MEN1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0908447-B1 | PROCESS FOR THE PREPARATION OF CYANOARYLMETHYLAMINE | SHOWA DENKO KK (JP) | 2007-03-28 | — | — | EP | disclosed |
| US-6114277-A | Process for preparing cyano group-containing aromatic methylamines | SHOWA DENKO K.K. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0908447-A1 | PROCESS FOR THE PREPARATION OF CYANOARYLMETHYLAMINE | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1999-04-14 | — | — | EP | disclosed |