Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5163803 | 1.00 | CES2 (0.50) | CES2CES1SLC6A3NR1I2TRPM8 | |
| SCHEMBL681159 | 0.84 | NPC1 (0.58) | CES2CES1NPC1MAPTSMN1; SMN2 | |
| SCHEMBL10894082 | 0.81 | TDP1 (0.61) | CES2CES1PTGS2PTGS1MAPT | |
| SCHEMBL702447 | 0.81 | TDP1 (0.61) | CES2CES1PTGS2PTGS1MAPT | |
| SCHEMBL19997374 | 0.80 | CES2 (0.72) | CES2CES1SLC6A3NR1I2TRPM8 | |
| SCHEMBL17483917 | 0.80 | NPC1 (0.50) | CES2CES1NPC1PTGS2SMN1; SMN2 | |
| SCHEMBL30076063 | 0.79 | CES2 (0.57) | CES2CES1PTGS2PTGS1MAPT | |
| SCHEMBL28956816 | 0.79 | CES2 (0.57) | CES2CES1PTGS2PTGS1MAPT | |
| SCHEMBL7211288 | 0.76 | PTGS2 (0.41) | CES2CES1PTGS2PTGS1MAPT | |
| SCHEMBL28277704 | 0.75 | HDAC3 (0.55) | MAPTSMN1; SMN2KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1371712-B1 | LIQUID-CRYSTAL COMPOSITION CONTAINING OPTICALLY ACTIVE COMPOUND AND LIQUID-CRYSTAL ELECTROOPTIC ELEMENT | SEIMI CHEM KK (JP) | 2007-04-11 | — | — | EP | disclosed |
| US-7108895-B2 | Liquid crystal composition containing an optically active compound and liquid crystal electro-optical element | SEIMI CHEMICAL CO., LTD. (JP) | 2006-09-19 | — | — | US | disclosed |
| EP-1650286-A2 | Liquid crystal composition containing an optically active compound and liquid crystal electro-optical element | Seimi Chemical Co., Ltd. (JP) | 2006-04-26 | — | — | EP | disclosed |
| EP-1650284-A2 | Liquid crystal composition containing an optical active compound and liquid crystal electro-optical element | Seimi Chemical Co., Ltd. (JP) | 2006-04-26 | — | — | EP | disclosed |
| EP-1650285-A2 | Liquid crystal composition containing an optically active compound and liquid crystal electro-optical element | Seimi Chemical Co., Ltd. (JP) | 2006-04-26 | — | — | EP | disclosed |
| US-20040079922-A1 | Liquid crystal composition containing an optically active compound and liquid crystal electro-optical element | SEIMI CHEMICAL CO., LTD. (JP) | 2004-04-29 | — | — | US | disclosed |
| EP-1371712-A1 | LIQUID-CRYSTAL COMPOSITION CONTAINING OPTICALLY ACTIVE COMPOUND AND LIQUID-CRYSTAL ELECTROOPTIC ELEMENT | Seimi Chemical Co., Ltd. (JP) | 2003-12-17 | — | — | EP | disclosed |