Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 6/20 | 0.59 |
| ▸ | CES2 | O00748 | 1/20 | 0.59 |
| ▸ | CES1 | P23141 | 1/20 | 0.59 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | HRH1 | P35367 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.52 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10894082 | 1.00 | TDP1 (0.61) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL4806377 | 0.88 | PTGS2 (0.69) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL8021929 | 0.88 | PTGS2 (0.54) | TDP1L3MBTL1LMNAPGRADRA2A | |
| SCHEMBL16162334 | 0.88 | CES2 (0.53) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL17483863 | 0.88 | PTGS2 (0.63) | TDP1L3MBTL1LMNAALDH1A1PTGS2 | |
| SCHEMBL28956932 | 0.88 | PTGS2 (0.63) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL2926204 | 0.88 | CES2 (0.53) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL9541003 | 0.88 | LMNA (0.53) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL9125050 | 0.88 | LMNA (0.62) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL4601940 | 0.86 | CES2 (0.52) | TDP1L3MBTL1LMNACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 425 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110272349-A | - 3 phenyl phenylpropyl alcohol ketone compound of a kind of 2 '-hydroxyl and its preparation method and application | 南阳师范学院 | 2019-09-24 | — | — | CN | claimed |
| CN-107325128-B | A kind of preparation method of DiDOPO class compound | 中国科学院宁波材料技术与工程研究所 | 2019-04-02 | — | — | CN | claimed |
| EP-2699218-B1 | USE OF A COMBINATION OF CAROTENOID, PHYTOESTROGEN AND VITAMIN C FOR THE PREVENTION AND/OR TREATMENT OF PIGMENTATION DISORDERS | NUTRICOS TECH (FR) | 2018-10-17 | — | — | EP | claimed |
| EP-2900336-B1 | ORAL COMPOSITION FOR REINFORCING SKIN TOLERANCE FOLLOWING TOPICAL ADMINISTRATION OF A RETINOID COMPOUND | NUTRICOS TECH (FR) | 2018-07-25 | — | — | EP | claimed |
| CN-108299237-A | A kind of synthetic method of methylene malononitrile derivative | 浙江工业大学 | 2018-07-20 | — | — | CN | claimed |
| US-10022315-B2 | Oral composition for reinforcing skin tolerance following topical administration of a retinoid compound | LABORATOIRES INNEOV (FR) | 2018-07-17 | — | — | US | claimed |
| CN-107722146-A | Method for producing solid polyaluminoxane composition | 三井化学株式会社 | 2018-02-23 | — | — | CN | claimed |
| US-9884936-B2 | Photoactive resins, radiation curable compositions and radiation curable inks | SUN CHEMICAL CORPORATION (US) | 2018-02-06 | — | — | US | claimed |
| CN-107325128-A | A kind of preparation method of DiDOPO classes compound | 中国科学院宁波材料技术与工程研究所 | 2017-11-07 | — | — | CN | claimed |
| EP-2785754-B1 | PHOTOACTIVE RESINS, RADIATION CURABLE COMPOSITIONS AND RADIATION CURABLE INKS | SUN CHEMICAL CORP (US) | 2016-07-06 | — | — | EP | claimed |
| CN-101184711-A | Nucleophilic heterocyclic carbene derivatives of pd(acac)2 for cross-coupling reactions | PROMERUS LLC (US) | 2008-05-21 | — | — | CN | claimed |
| EP-1885669-A1 | NUCLEOPHILIC HETEROCYCLIC CARBENE DERIVATIVES OF PD(ACAC)2 FOR CROSS-COUPLING REACTIONS | Promerus LLC (US) | 2008-02-13 | — | — | EP | claimed |
| CN-101095462-A | Method for synthesizing the feed additive - isoflavone | GUANGDONG XINNANDU FEED TECHNO (CN) | 2008-01-02 | — | — | CN | claimed |
| CN-101002946-A | Medicine for treating tumor and application thereof | UNIV TSINGHUA (CN) | 2007-07-25 | — | — | CN | claimed |
| US-20060287544-A1 | Nucleophilic heterocyclic carbene derivatives of Pd(acac)2 for cross-coupling reactions | PROMERUS LLC (US) | 2006-12-21 | — | — | US | claimed |
| WO-2006128097-A1 | NUCLEOPHILIC HETEROCYCLIC CARBENE DERIVATIVES OF PD(ACAC)2 FOR CROSS-COUPLING REACTIONS | PROMERUS LLC (US) | 2006-11-30 | — | — | WO | claimed |
| US-20040071745-A1 | Admixture of carotenoids and isoflavonoids for treating cutaneous symptoms of aging | SOCIETE L'OREAL S.A. (FR) | 2004-04-15 | — | — | US | claimed |
| US-20020197289-A1 | Compositions and methods for combating the appearance of ageing | L'OREAL (FR) | 2002-12-26 | — | — | US | claimed |
| US-20020192289-A1 | Polymer gel for cancer treatment | ZHENG JI (US) | 2002-12-19 | — | — | US | claimed |
| EP-1262168-A1 | Composition containing fibres to combat the skin aging process | L'OREAL (FR) | 2002-12-04 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020197289-A1 | Compositions and methods for combating the appearance of ageing | CYP24A1, CYP27B1, CYP2R1 | TDP1 1203/4885L3MBTL1 3891/4885LMNA 970/4885 |
| US-20060287544-A1 | Nucleophilic heterocyclic carbene derivatives of Pd(acac)2 for cross-coupling reactions | NDC1, DDC, PDCD1LG2 | TDP1 3665/4885L3MBTL1 3889/4885LMNA 4016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.