Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2568266 | 0.93 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL139125 | 0.86 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL7718185 | 0.85 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3305049 | 0.82 | TDP1 (0.45) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3158160 | 0.82 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL7880357 | 0.82 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL98029 | 0.81 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28363432 | 0.81 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL6765015 | 0.81 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL19409198 | 0.80 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1211278-B1 | Organic - inorganic composite particles and production process thereof | NIPPON CATALYTIC CHEM IND (JP) | 2007-03-21 | — | — | EP | disclosed |
| EP-1211278-A2 | Organic - inorganic composite particles and production process thereof | NIPPON SHOKUBAI CO., LTD. (JP) | 2002-06-05 | — | — | EP | disclosed |