SCHEMBL3305049

SCHEMBL3305049

C=C(C)C(=O)OCCC[SiH](Cc1ccccc1)OCC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.45
POLB P06746 1/20 0.45
APEX1 P27695 1/20 0.45
HTT P42858 1/20 0.45
TSHR P16473 5/20 0.42
THRB P10828 1/20 0.40
ALDH1A1 P00352 4/20 0.36
MAPT P10636 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
CYP3A4 P08684 2/20 0.36
MAPK1 P28482 2/20 0.36
LMNA P02545 2/20 0.35
RECQL P46063 2/20 0.33
ELANE P08246 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3309530 0.87 TDP1 (0.47) TDP1POLBAPEX1HTTTSHR
SCHEMBL9422121 0.82 THRB (0.45) TDP1TSHRTHRBALDH1A1MAPT
SCHEMBL5164067 0.82 TSHR (0.56) TDP1POLBAPEX1HTTTSHR
SCHEMBL3306606 0.82 TDP1 (0.49) TDP1POLBAPEX1HTTTSHR
SCHEMBL10455438 0.81 TDP1 (0.38) TDP1POLBAPEX1HTTTSHR
SCHEMBL2568266 0.80 TSHR (0.53) TDP1POLBAPEX1HTTTSHR
SCHEMBL148938 0.75 LMNA (0.60) TDP1POLBAPEX1HTTTSHR
SCHEMBL7876635 0.75 TSHR (0.35) POLBTSHRALDH1A1MAPTL3MBTL1
SCHEMBL5074140 0.74 TDP1 (0.50) TDP1POLBAPEX1HTTTSHR
SCHEMBL146245 0.74 POLB (0.55) TDP1POLBAPEX1HTTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5886082-A AQUEOUS DISPERSION OF ACRYLIC POLYMER, POLYURETHANE RESIN, POLYISOCYANATE; WATER RESISTANCE, ADHESION KANSAI PAINT CO., LTD. (JP) 1999-03-23 US claimed
EP-0665252-B1 Two-pack aqueous coating composition KANSAI PAINT CO LTD (JP) 1998-12-16 EP claimed
CN-109476964-B Polymeric binder layer as a ceramic precursor 3M创新有限公司 2022-04-26 CN disclosed
US-20220119692-A1 DUST SUPPRESSION COMPOSITIONS AND METHODS 3M INNOVATIVE PROPERTIES CO (US) 2022-04-21 US disclosed
US-11292940-B2 Polymeric adhesive layers as ceramic precursors 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-04-05 US disclosed
US-11285702-B2 Siloxane-based adhesive layers as ceramic precursors 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-03-29 US disclosed
CN-109642143-B Siloxane-based adhesive layer as a ceramic precursor 3M创新有限公司 2021-09-24 CN disclosed
US-10947396-B2 Curable antifouling composition, method of use, and articles 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-03-16 US disclosed
US-20190352542-A1 POLYMERIC ADHESIVE LAYERS AS CERAMIC PRECURSORS 3M INNOVATIVE PROPERTIES COMPANY 2019-11-21 US disclosed
US-20190300634-A1 DUST SUPPRESSION COMPOSITIONS AND METHODS 3M INNOVATIVE PROPERTIES COMPANY 2019-10-03 US disclosed
US-20190218425-A1 SILOXANE-BASED ADHESIVE LAYERS AS CERAMIC PRECURSORS 3M INNOVATIVE PROPERTIES COMPANY 2019-07-18 US disclosed
US-5130167-A For automobiles, vinyl polymers containing silicon groups, epoxy groups and hydroxy groups KANSAI PAINT COMPANY, LIMITED (JP) 1992-07-14 US disclosed
EP-0484540-A1 AUTOMOTIVE TOPCOATING COMPOSITION KANSAI PAINT CO., LIMITED (JP) 1992-05-13 EP disclosed
EP-0308203-B1 CURABLE COMPOSITION KANSAI PAINT CO., LTD. (JP) 1992-01-29 EP disclosed
US-5026793-A Containing hydroxy, epoxy, and silane compounds with chelate compound containing aluminum, titanium, or zironium KANSAI PAINT COMPANY LIMITED (JP) 1991-06-25 US disclosed
US-4972027-A UNSATURATED MONOMERS POLYMERIZED IN THE PRESENCE OF A STABILIZER RESIN, A COPOLYMER OF AN OXIRANE CONTAINING VINYL MONOMER AND AN ALKOXYSILANE VINYL MONOMER, A POLYSILOXANE KANSAI PAINT COMPANY, LIMITED (JP) 1990-11-20 US disclosed
US-4927884-A POLYSILOXANE, EPOXY-VINYL, CHELATE COMPOUND KANSAI PAINT CO., LIMITED (JP) 1990-05-22 US disclosed
US-4923945-A Oxirane containing vinyl monomer and alkoxysilane containing vinyl monomer KANSAI PAINT COMPANY, LIMITED (JP) 1990-05-08 US disclosed
US-4923930-A VINYLALKOXYSILANE, POLYSILOXANE, VINYL EPOXIDE KANSAI PAINT COMPANY, LIMITED (JP) 1990-05-08 US disclosed
US-4772672-A COATINGS KANSAI PAINT COMPANY, LIMITED (JP) 1988-09-20 US disclosed