SCHEMBL516430

SCHEMBL516430

Cc1nc2[nH]c(=S)n(C)c(=O)c2[nH]1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE2A O00408 1/20 0.44
PDE1A P54750 1/20 0.44
PDE1B Q01064 1/20 0.44
PDE1C Q14123 1/20 0.44
MAPT P10636 4/20 0.40
ALDH1A1 P00352 2/20 0.40
HPGD P15428 1/20 0.40
ADORA2B P29275 3/20 0.39
ADORA2A P29274 2/20 0.39
KDM4E B2RXH2 2/20 0.38
CYP3A4 P08684 2/20 0.36
CYP2C19 P33261 2/20 0.36
LGMN Q99538 1/20 0.36
KDM4A O75164 1/20 0.35
POLB P06746 1/20 0.35
KDM4C Q9H3R0 1/20 0.35
GAA P10253 2/20 0.35
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
CYP1A1 P04798 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL387340 0.81 ADORA2B (0.55) PDE2APDE1APDE1BPDE1CMAPT
SCHEMBL5406879 0.71 HPGD (0.56) PDE2APDE1APDE1BPDE1CMAPT
SCHEMBL515533 0.71 CYP3A4 (0.62) PDE2APDE1APDE1BPDE1CMAPT
SCHEMBL6381402 0.69 ADORA2B (0.36) PDE2APDE1APDE1BPDE1CADORA2B
SCHEMBL23607958 0.68 MAPT (0.37) MAPTALDH1A1HPGDADORA2BADORA2A
SCHEMBL22521968 0.68 CYP2C9 (0.61) MAPTALDH1A1HPGDKDM4ECYP3A4
SCHEMBL150604 0.67 PDE1A (0.54) PDE2APDE1APDE1BPDE1CADORA2B
SCHEMBL461786 0.67 PDE2A (0.62) PDE2APDE1APDE1BPDE1CALDH1A1
Water SCHEMBL28799658 0.66 PDE2A (0.60) PDE2APDE1APDE1BPDE1CALDH1A1
Theobromine SCHEMBL2328879 0.65 CYP3A4 (0.66) MAPTALDH1A1ADORA2BADORA2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250386846-A1 Food Compositions Including Aragonite NANT HOLDINGS IP LLC (US) 2025-12-25 US disclosed
US-12419336-B2 Beverage compositions including calcium supplied from aragonite and methods of making the same NANT HOLDINGS IP, LLC (US) 2025-09-23 US disclosed
US-20250194654-A1 Beverage Compositions Including Calcium Supplied From Aragonite And Methods Of Making The Same NANT HOLDINGS IP, LLC 2025-06-19 US disclosed
US-12310392-B2 Beverage compositions including calcium supplied from aragonite and methods of making the same NANT HOLDINGS IP, LLC (US) 2025-05-27 US disclosed
US-20240381918-A1 Beverage Compositions Including Calcium Supplied From Aragonite And Methods Of Making The Same NANT HOLDINGS IP, LLC 2024-11-21 US disclosed
US-12089621-B2 Beverage compositions including calcium supplied from aragonite and methods of making the same NANT HOLDINGS IP, LLC (US) 2024-09-17 US disclosed
US-20230354865-A1 Beverage Compositions Including Calcium Supplied From Aragonite And Methods Of Making The Same NANT HOLDINGS IP, LLC 2023-11-09 US disclosed
US-11793224-B2 Beverage compositions including calcium supplied from aragonite and methods of making the same NANT HOLDINGS IP, LLC (US) 2023-10-24 US disclosed
US-20230085907-A1 Beverage Compositions Including Calcium Supplied From Aragonite And Methods Of Making The Same NANT HOLDINGS IP, LLC 2023-03-23 US disclosed
US-11533940-B2 Beverage compositions including calcium supplied from aragonite and methods of making the same NANT HOLDINGS IP, LLC (US) 2022-12-27 US disclosed
EP-1289531-A2 KITS AND METHODS FOR OPTIMIZING THE EFFICACY OF CHONDROPROTECTIVE COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2003-03-12 EP disclosed
US-20020187219-A1 Low glycemic response compositions THE PROCTER & GAMBLE CO. 2002-12-12 US disclosed
US-20020136802-A1 Beverage compositions comprising arabinogalactan and defined minerals THE PROCTER & GAMBLE CO. 2002-09-26 US disclosed
US-20020132780-A1 Low carbohydrate compositions, kits thereof, and methods of use SD IP HOLDINGS COMPANY 2002-09-19 US disclosed
US-20020122847-A1 Beverage compositions comprising palatable calcium and magnesium sources PROCTER & GAMBLE COMPANY, THE 2002-09-05 US disclosed
US-20020110632-A1 Beverage compositions comprising arabinogalactan and defined vitamins THE PROCTER & GAMBLE CO. 2002-08-15 US disclosed
US-6413558-B1 MIXTURE OF MONOSACCHARIDES, DISACCHARIDES AND MALTODEXTRIN THE PROCTOR & GAMBLE CO. 2002-07-02 US disclosed
WO-2001093832-A2 AQUEOUS CHONDROPROTECTIVE COMPOSITIONS HAVING DEFINED DOSAGE REQUIREMENTS FOR EFFICACIOUS DELIVERY THE PROCTER & GAMBLE COMPANY (US) 2001-12-13 WO disclosed
WO-2001093833-A2 KITS AND METHODS FOR OPTIMIZING THE EFFICACY OF CHONDROPROTECTIVE COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2001-12-13 WO disclosed
WO-2001093701-A2 AQUEOUS CHONDROPROTECTIVE COMPOSITIONS HAVING DEFINED PH LIMITATIONS FOR EFFICACIOUS DELIVERY THE PROCTER & GAMBLE COMPANY (US) 2001-12-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250386846-A1 Food Compositions Including Aragonite PLCG2, PLCG1, PLCB3 PDE2A 3038/4885PDE1A 556/4885PDE1B 397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.