Hydrochloric Acid

Hydrochloric Acid

SCHEMBL516449

C[N+](C)(CCO)C(N)=O.[Cl-]

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 known ✓ P11229 3/20 0.39
CHRM3 known ✓ P20309 3/20 0.39
CHRM2 known ✓ P08172 2/20 0.39
CYP3A4 P08684 1/20 0.48
SLC5A7 Q9GZV3 1/20 0.48
LMNA P02545 4/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
CHRM5 P08912 3/20 0.39
CHRM4 P08173 2/20 0.39
HTR1A P08908 1/20 0.36
TSHR P16473 1/20 0.36
CHRNB2 P17787 1/20 0.36
CYP2C19 P33261 1/20 0.36
CHRNA7 P36544 1/20 0.36
CHRNA4 P43681 1/20 0.36
MAPT P10636 2/20 0.32
ALDH1A1 P00352 1/20 0.32
APEX1 P27695 1/20 0.32
PSMD14 O00487 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4252733 0.97
Choline SCHEMBL516453 0.78 CYP3A4 (0.72) CYP3A4SLC5A7LMNAMEN1KMT2A
Choline SCHEMBL28308438 0.78 CYP3A4 (0.72) CYP3A4SLC5A7LMNAMEN1KMT2A
Choline SCHEMBL28248281 0.76 CYP3A4 (0.68) CYP3A4SLC5A7LMNAMEN1KMT2A
Hydrochloric Acid SCHEMBL4728224 0.76 CYP3A4 (0.46) CYP3A4SLC5A7LMNAMEN1KMT2A
Choline SCHEMBL28036788 0.76 CYP3A4 (0.68) CYP3A4SLC5A7LMNAMEN1KMT2A
Choline SCHEMBL15993921 0.76 CYP3A4 (0.68) CYP3A4SLC5A7LMNAMEN1KMT2A
Choline SCHEMBL16106188 0.76 CYP3A4 (0.68) CYP3A4SLC5A7LMNAMEN1KMT2A
Choline SCHEMBL4211637 0.76 CYP3A4 (0.68) CYP3A4SLC5A7LMNAMEN1KMT2A
SCHEMBL8679788 0.75 TDP1 (0.36) CYP3A4SLC5A7LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120028855-A1 SHALE HYDRATION INHIBITION AGENT(S) AND METHOD OF USE SHRIEVE CHEMICAL PRODUCTS (US) 2012-02-02 US disclosed
US-8022014-B2 Deep eutectic solvents and applications SHRIEVE CHEMICAL PRODUCTS, INC. 2011-09-20 US disclosed
US-20110207633-A1 DEEP EUTECTIC SOLVENTS AND APPLICATIONS SHRIEVE CHEMICAL PRODUCTS, INC. (US) 2011-08-25 US disclosed
US-20090247432-A1 DEEP EUTECTIC SOLVENTS AND APPLICATIONS SHRIEVE CHEMICAL PRODUCTS, INC. (US) 2009-10-01 US disclosed
WO-2009120839-A2 DEEP EUTECTIC SOLVENTS AND APPLICATIONS SHRIEVE CHEMICAL PRODUCTS, INC. (US) 2009-10-01 WO disclosed