Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 15/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28154281 | 0.62 | DPP4 (0.53) | DPP4DPP8PLA2G7 | |
| SCHEMBL4753134 | 0.62 | CES1 (0.44) | CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL28845596 | 0.61 | DPP4 (0.52) | DPP4DPP8PLA2G7 | |
| SCHEMBL1995182 | 0.61 | DPP4 (0.52) | DPP4DPP8HSP90AA1 | |
| SCHEMBL28589830 | 0.61 | PLA2G7 (0.48) | CYP1A1CYP1A2PLA2G7TNKS2 | |
| SCHEMBL28110786 | 0.61 | PLA2G7 (0.52) | DPP4CYP1A1CYP1A2PLA2G7 | |
| SCHEMBL1999197 | 0.59 | DPP4 (0.51) | DPP4DPP8 | |
| SCHEMBL521542 | 0.59 | PLA2G7 (0.50) | DPP4CYP1A1CYP1A2PLA2G7 | |
| SCHEMBL9602432 | 0.59 | DPP4 (0.50) | DPP4DPP8CYP1A1CYP1A2DPP9 | |
| SCHEMBL2787484 | 0.59 | CA1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753730-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2007-02-21 | — | — | EP | claimed |
| WO-2005118555-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-12-15 | — | — | WO | claimed |