Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.52 |
| ▸ | MYC | P01106 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL521542 | 0.93 | PLA2G7 (0.50) | PLA2G7MYCGAAMGAMSI | |
| SCHEMBL2232919 | 0.91 | PLA2G7 (0.53) | PLA2G7MYCGAAMGAMSI | |
| SCHEMBL9678940 | 0.87 | ALDH1A1 (0.52) | PLA2G7GAAMGAMSIMGAM2 | |
| SCHEMBL13201408 | 0.86 | ALDH1A1 (0.46) | PLA2G7MYCGAAMGAMSI | |
| SCHEMBL28589830 | 0.82 | PLA2G7 (0.48) | PLA2G7ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL28899579 | 0.82 | MYC (0.58) | MYCALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5281695 | 0.81 | PLA2G7 (0.47) | PLA2G7MYCGAAMGAMSI | |
| SCHEMBL321560 | 0.80 | PLA2G7 (0.61) | PLA2G7GAAMGAMSIMGAM2 | |
| SCHEMBL16589092 | 0.80 | ALDH1A1 (0.47) | PLA2G7GAAALDH1A1LMNAKDM4E | |
| SCHEMBL3834191 | 0.80 | MYC (0.53) | MYCGAAALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106132414-A | Aryl lactams inhibitors of kinases | 百时美施贵宝公司 | 2016-11-16 | — | — | CN | disclosed |