Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 9/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5369759 | 0.99 | OPRM1 (0.47) | OPRM1OPRL1MTNR1AIDO1GRIN2B | |
| Hydrochloric Acid SCHEMBL5164843 | 0.99 | OPRM1 (0.47) | OPRM1OPRL1MTNR1AIDO1GRIN2B | |
| SCHEMBL5166608 | 0.89 | OPRM1 (0.44) | OPRM1OPRL1GRIN2BOPRK1C5AR1 | |
| Hydrochloric Acid SCHEMBL5163755 | 0.88 | OPRM1 (0.46) | OPRM1OPRL1GRIN2BOPRK1C5AR1 | |
| SCHEMBL5168202 | 0.83 | OPRL1 (0.64) | OPRM1OPRL1MTNR1AIDO1OPRK1 | |
| Hydrochloric Acid SCHEMBL5165488 | 0.82 | OPRL1 (0.64) | OPRM1OPRL1MTNR1AIDO1 | |
| Hydrochloric Acid SCHEMBL5166660 | 0.82 | OPRL1 (0.64) | OPRM1OPRL1MTNR1AIDO1 | |
| SCHEMBL25029914 | 0.80 | MTNR1A (0.58) | MTNR1AIDO1GRIN2BMEN1KMT2A | |
| SCHEMBL5166242 | 0.76 | OPRM1 (0.51) | OPRM1OPRL1GRIN2BOPRK1MEN1 | |
| SCHEMBL5165079 | 0.74 | OPRM1 (0.65) | OPRM1OPRL1GRIN2BOPRK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392641-B1 | SUBSTITUTED CYCLOHEXANE-1,4-DIAMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2007-04-11 | — | — | EP | claimed |