SCHEMBL5164558

SCHEMBL5164558

CCCOCC([O])=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5772685 0.83
SCHEMBL17351008 0.81 CES2 (0.68)
SCHEMBL2241590 0.80
SCHEMBL8383900 0.80
SCHEMBL8735593 0.80 ALDH1A1 (0.54)
SCHEMBL295696 0.80
SCHEMBL7054188 0.79
SCHEMBL4444502 0.79
SCHEMBL10339699 0.78
SCHEMBL8379389 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9263767-B2 Electrolyte solution for electrochemical devices WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2016-02-16 US disclosed
US-20140162143-A1 ELECTROLYTE SOLUTION FOR ELECTROCHEMICAL DEVICES WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2014-06-12 US disclosed
EP-2738862-A1 ELECTROLYTE SOLUTION FOR ELECTROCHEMICAL DEVICES Wako Pure Chemical Industries, Ltd. (JP) 2014-06-04 EP disclosed
EP-1772150-A1 Benzothiophene formulations of a specific dosage Eli Lilly &amp; Company (US) 2007-04-11 EP disclosed
US-20060106010-A1 Methods for inhibiting bone loss ELI LILLY AND COMPANY 2006-05-18 US disclosed
US-RE39049-E1 Methods for inhibiting bone loss ELI LILLY AND COMPANY (US) 2006-03-28 US disclosed
US-RE38968-E1 Methods for inhibiting bone loss using 6-hydroxy-2-(4-hydroxyphenyl)-benzo[b]thien-3-yl-4-[2-(piperidin-1-yl) ethoxyphenylimethanone hydrochloride ELI LILLY AND COMPANY (US) 2006-02-07 US disclosed
US-6906086-B2 Methods for inhibiting bone loss ELI LILLY AND COMPANY (US) 2005-06-14 US disclosed
EP-1438957-A1 Benzothiophene formulations of a specific dosage ELI LILLY AND COMPANY (US) 2004-07-21 EP disclosed
US-20030212058-A1 Methods for inhibiting bone loss ELI LILLY AND COMPANY 2003-11-13 US disclosed
EP-0651998-A1 Methods for inhibiting bone loss ELI LILLY AND COMPANY (US) 1995-05-10 EP disclosed
EP-0650724-A1 Methods for inhibiting uterine fibrosis ELI LILLY AND COMPANY (US) 1995-05-03 EP disclosed
US-5393763-A Administering benzothiophenes such as raloxifene hydrochloride ELI LILLY AND COMPANY (US) 1995-02-28 US disclosed
EP-0635264-A2 Antiestrogens as hypoglycemic agents ELI LILLY AND COMPANY (US) 1995-01-25 EP disclosed
EP-0605193-A1 Use of benzothiophenes for treatment of hypercholesterolaemia ELI LILLY AND COMPANY (US) 1994-07-06 EP disclosed
EP-0587311-A1 Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use SANKYO COMPANY LIMITED (JP) 1994-03-16 EP disclosed
EP-0584952-A1 Improvements in or relating to benzothiophenes ELI LILLY AND COMPANY (US) 1994-03-02 EP disclosed
US-4556737-A ANTIALLERGENS, TREATMENT OF ASTHMA AND RHINITIS TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) 1985-12-03 US disclosed
US-4415494-A BLUE-TO-BLACK COLORFAST DISPERSE, NITRO DYES; DIAZOTIZING A P-NITROANILINE AND COUPLING WITH AN N-SUBSTITUTED 1-NAPHTHYLAMINE CASSELLA AKTIENGESELLSCHAFT (DE) 1983-11-15 US disclosed
EP-0036545-A1 Water insoluble monoazo dyes, their preparation and their use CASSELLA Aktiengesellschaft (DE) 1981-09-30 EP disclosed