SCHEMBL5164574

SCHEMBL5164574

Nc1ccc(O)cc1CC(=O)NCc1ccco1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 6/20 0.53
ALDH1A1 P00352 8/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
POLB P06746 5/20 0.50
KDM4E B2RXH2 4/20 0.50
HSD17B10 Q99714 3/20 0.50
TSHR P16473 3/20 0.50
NPC1 O15118 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
LMNA P02545 2/20 0.50
MAPT P10636 1/20 0.50
PTPN7 P35236 1/20 0.50
USP2 O75604 1/20 0.50
S1PR2 O95136 1/20 0.47
S1PR4 O95977 1/20 0.47
ESR1 P03372 1/20 0.47
TP53 P04637 1/20 0.47
GLA P06280 1/20 0.47
GAA P10253 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5095911 0.81 HSD17B10 (0.55) HPGDALDH1A1MEN1KMT2APOLB
SCHEMBL5162927 0.80 POLB (0.57) HPGDALDH1A1MEN1KMT2APOLB
Ammonia Solution, Strong SCHEMBL5307186 0.79 POLB (0.56) HPGDALDH1A1MEN1KMT2APOLB
SCHEMBL5162641 0.78 ALDH1A1 (0.51) HPGDALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL5162190 0.76 MEN1 (0.40) HPGDMEN1KMT2A
SCHEMBL22664788 0.75 HPGD (0.58) HPGDALDH1A1MEN1KMT2APOLB
SCHEMBL6095562 0.75 HPGD (0.60) HPGDALDH1A1MEN1KMT2APOLB
SCHEMBL6095566 0.75 HPGD (0.60) HPGDALDH1A1MEN1KMT2APOLB
SCHEMBL11628059 0.75 POLB (0.64) HPGDALDH1A1MEN1KMT2APOLB
SCHEMBL29410065 0.75 ALDH1A1 (0.74) HPGDALDH1A1MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070067922-A1 4-Aminophenol derivatives and colorants comprising these compounds PROCTER & GAMBLE COMPANY, THE 2007-03-29 US claimed
EP-1762218-A1 4-aminophenol derivatives and colorants comprising these compounds Wella Aktiengesellschaft (DE) 2007-03-14 EP claimed
WO-2007026313-A2 4-AMINOPHENOL DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2007-03-08 WO claimed
US-20070067922-A1 4-Aminophenol derivatives and colorants comprising these compounds PROCTER & GAMBLE COMPANY, THE 2007-03-29 US disclosed
EP-1762218-A1 4-aminophenol derivatives and colorants comprising these compounds Wella Aktiengesellschaft (DE) 2007-03-14 EP disclosed
WO-2007026313-A2 4-AMINOPHENOL DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2007-03-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070067922-A1 4-Aminophenol derivatives and colorants comprising these compounds KRT18, S100A4, CKAP4 HPGD 565/4885ALDH1A1 309/4885MEN1 4874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.