Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5162927 | 0.99 | POLB (0.57) | POLBNPC1HPGDALDH1A1MEN1 | |
| SCHEMBL22664788 | 0.81 | HPGD (0.58) | POLBNPC1HPGDALDH1A1MEN1 | |
| SCHEMBL11628059 | 0.80 | POLB (0.64) | POLBNPC1HPGDALDH1A1MEN1 | |
| SCHEMBL5164574 | 0.79 | HPGD (0.53) | POLBNPC1HPGDALDH1A1MEN1 | |
| SCHEMBL5161911 | 0.76 | ALDH1A1 (0.53) | NPC1HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL5095911 | 0.75 | HSD17B10 (0.55) | POLBNPC1HPGDALDH1A1MEN1 | |
| SCHEMBL29410065 | 0.75 | ALDH1A1 (0.74) | POLBHPGDALDH1A1MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL5332401 | 0.75 | GAA (0.35) | POLBHPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL5162095 | 0.74 | EPHX2 (0.39) | POLBHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL14511323 | 0.74 | ALDH1A1 (0.68) | POLBNPC1HPGDALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007026312-A1 | 1,3-DIAMINOBENZENE DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2007-03-08 | — | — | WO | disclosed |