Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5162662 | 0.86 | NLRP3 (0.54) | NLRP3KMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL5164495 | 0.86 | NLRP3 (0.56) | NLRP3KMT2AMEN1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL5163148 | 0.84 | NLRP3 (0.55) | NLRP3KMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL5165552 | 0.84 | NLRP3 (0.54) | NLRP3KMT2AMEN1HPGDSMN1; SMN2 | |
| SCHEMBL3815239 | 0.82 | CYP1A2 (0.53) | NLRP3KMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL5162820 | 0.81 | USP2 (0.61) | USP2KMT2AMEN1HPGDSMN1; SMN2 | |
| SCHEMBL5159531 | 0.81 | NLRP3 (0.54) | NLRP3KMT2AMEN1HPGDSMN1; SMN2 | |
| SCHEMBL5162730 | 0.81 | KCNJ5 (0.61) | NLRP3KMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL5159570 | 0.81 | KMT2A (0.57) | NLRP3KMT2AMEN1HPGDSMN1; SMN2 | |
| SCHEMBL8705939 | 0.81 | USP2 (0.80) | USP2NLRP3KMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070067922-A1 | 4-Aminophenol derivatives and colorants comprising these compounds | PROCTER & GAMBLE COMPANY, THE | 2007-03-29 | — | — | US | claimed |
| EP-1762218-A1 | 4-aminophenol derivatives and colorants comprising these compounds | Wella Aktiengesellschaft (DE) | 2007-03-14 | — | — | EP | claimed |
| WO-2007026313-A2 | 4-AMINOPHENOL DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2007-03-08 | — | — | WO | claimed |
| US-20070067922-A1 | 4-Aminophenol derivatives and colorants comprising these compounds | PROCTER & GAMBLE COMPANY, THE | 2007-03-29 | — | — | US | disclosed |
| EP-1762218-A1 | 4-aminophenol derivatives and colorants comprising these compounds | Wella Aktiengesellschaft (DE) | 2007-03-14 | — | — | EP | disclosed |
| WO-2007026313-A2 | 4-AMINOPHENOL DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2007-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070067922-A1 | 4-Aminophenol derivatives and colorants comprising these compounds | KRT18, S100A4, CKAP4 | USP2 4037/4885NLRP3 4180/4885KMT2A 1287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.