Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 15/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.46 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL5163148 | 0.99 | NLRP3 (0.55) | NLRP3HDAC4ALDH1A1CYP1A2KMT2A | |
| SCHEMBL3815239 | 0.90 | CYP1A2 (0.53) | NLRP3HDAC4CYP1A2KMT2AMEN1 | |
| SCHEMBL5159570 | 0.89 | KMT2A (0.57) | NLRP3ALDH1A1KMT2AMEN1 | |
| SCHEMBL5159531 | 0.89 | NLRP3 (0.54) | NLRP3ALDH1A1KMT2AMEN1 | |
| SCHEMBL5162730 | 0.89 | KCNJ5 (0.61) | NLRP3ALDH1A1KMT2AMEN1KCNJ5 | |
| SCHEMBL5165552 | 0.89 | NLRP3 (0.54) | NLRP3HDAC4ALDH1A1CYP1A2KMT2A | |
| SCHEMBL5162086 | 0.87 | ALDH1A1 (0.61) | ALDH1A1CYP1A2KMT2AMEN1 | |
| SCHEMBL5163021 | 0.86 | CYP1A1 (0.47) | NLRP3HDAC4ALDH1A1CYP1A2KMT2A | |
| SCHEMBL5162186 | 0.86 | ALDH1A1 (0.56) | NLRP3ALDH1A1KMT2AMEN1 | |
| SCHEMBL5162228 | 0.86 | LMNA (0.60) | ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070067922-A1 | 4-Aminophenol derivatives and colorants comprising these compounds | PROCTER & GAMBLE COMPANY, THE | 2007-03-29 | — | — | US | claimed |
| EP-1762218-A1 | 4-aminophenol derivatives and colorants comprising these compounds | Wella Aktiengesellschaft (DE) | 2007-03-14 | — | — | EP | claimed |
| WO-2007026313-A2 | 4-AMINOPHENOL DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2007-03-08 | — | — | WO | claimed |
| US-20070067922-A1 | 4-Aminophenol derivatives and colorants comprising these compounds | PROCTER & GAMBLE COMPANY, THE | 2007-03-29 | — | — | US | disclosed |
| EP-1762218-A1 | 4-aminophenol derivatives and colorants comprising these compounds | Wella Aktiengesellschaft (DE) | 2007-03-14 | — | — | EP | disclosed |
| WO-2007026313-A2 | 4-AMINOPHENOL DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2007-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070067922-A1 | 4-Aminophenol derivatives and colorants comprising these compounds | KRT18, S100A4, CKAP4 | NLRP3 4180/4885HDAC4 310/4885ALDH1A1 309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.